Evidence map›Paper›PMID 40715920›Full record

ArticleDiscover oncology2025

Targeted therapy for Wilms tumor: a bibliometric study of worldwide scientific activity and collaborative networks.

Boshen Shu, Shufeng Zhang, Jian Gao, Lin Wang, Xiaohui Wang

Abstract read
In one paragraph

Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Boshen ShuDepartment of Pediatric Surgery, Henan Provincial People's Hospital, Zhengzhou, 450003, Henan Province, China.
Shufeng ZhangDepartment of Pediatric Surgery, Henan Provincial People's Hospital, Zhengzhou, 450003, Henan Province, China.
Jian GaoDepartment of Pediatric Surgery, Henan Provincial People's Hospital, Zhengzhou, 450003, Henan Province, China.
Lin WangDepartment of Pediatric Surgery, Henan Provincial People's Hospital, Zhengzhou, 450003, Henan Province, China.
Xiaohui WangDepartment of Pediatric Surgery, Henan Provincial People's Hospital, Zhengzhou, 450003, Henan Province, China. 7655100@qq.com.

Funding

Natural Science Foundation of Henan Province 252300421371
6 · The paper itself

Abstract

background and purposeWilms tumor (WT), or nephroblastoma, is the most common abdominal solid tumor in children with a recurrence rate as high as 15%. Targeted therapy is an effective treatment choice for patients with WT. This study aimed to evaluate the global research activity and collaborative networks of WT targeted therapy through the bibliometric analysis.

methodsThe Web of Science Core Collection (WoSCC) database was used to search related studies on targeted therapy for WT published between 1945 and 2024. Subsequently, the VOSviewer, Graphpad, and Bibliometrix package in the R Studio were applied to conduct bibliometric and visualized analysis.

resultsA total of 1,604 publications were included in our analysis. The USA (n = 572) took the dominant position in the number of publications and Harvard University contributed most papers (n = 122). Sugiyama H and Oka Y demonstrated superior performance in this domain, with Sugiyama H leading in the number of publications (n = 59) and Oka Y leading in terms of co-citations (n = 382). The most productive journal was the Oncogene (n = 44). "Expression" and "Wilms Tumor" were the most frequent keywords, while "lncRNA", "Biomarkers" and "microRNA" were recent hotspots.

conclusionsResearch on targeted therapy for WT has developed rapidly with increasing interests, which emphasizes its growing importance in the scientific community. Nonetheless, the primary research has been primarily concentrated in a limited number of developed regions, and global collaboration remains inadequate. International collaborations and translational research should be reinforced to facilitate further advancements in this field.

Indexed as

BibliometricsGlobal collaborationNephroblastomaVisualized analysisVOSviewerWilms tumor

Identifiers

PMID40715920
PMCPMC12297111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.