Evidence map›Paper›PMID 40715851›Full record

ArticleBrain topography2025

Neural Correlates of Inhibitory Control in Children: Evidence Using MRI and fNIRS.

Leela Shah, Xin Zhou, Marissa Ann DiPiero, Jayse Merle Weaver, Corrina Frye, Steven R Kecskemeti, Ruth Y Litovsky, Andrew L Alexander, Elizabeth M Planalp, Douglas C Dean

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain topography, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Leela ShahWaisman Center, University of Wisconsin-Madison, 1500 Highland Ave, Madison, WI, 53705, USA. lshah4@wisc.edu.
Xin ZhouBrain and Mind Institute, The Chinese University of Hong Kong, 4 F, Hui Yeung Shing Building, N.T, Hong Kong, Hong Kong.
Marissa Ann DiPieroWaisman Center, University of Wisconsin-Madison, 1500 Highland Ave, Madison, WI, 53705, USA.
Jayse Merle WeaverWaisman Center, University of Wisconsin-Madison, 1500 Highland Ave, Madison, WI, 53705, USA.
Corrina FryeWaisman Center, University of Wisconsin-Madison, 1500 Highland Ave, Madison, WI, 53705, USA.
Steven R KecskemetiWaisman Center, University of Wisconsin-Madison, 1500 Highland Ave, Madison, WI, 53705, USA.
Ruth Y LitovskyWaisman Center, University of Wisconsin-Madison, 1500 Highland Ave, Madison, WI, 53705, USA.
Andrew L AlexanderWaisman Center, University of Wisconsin-Madison, 1500 Highland Ave, Madison, WI, 53705, USA.
Elizabeth M PlanalpWaisman Center, University of Wisconsin-Madison, 1500 Highland Ave, Madison, WI, 53705, USA.
Douglas C DeanWaisman Center, University of Wisconsin-Madison, 1500 Highland Ave, Madison, WI, 53705, USA.

Funding

Directional Hearing in Complex Auditory EnvironmentsR01DC003083 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI LITOVSKY, RUTH Y · 2004 to 2020
$7.4M
Integrated Training For Physician-ScientistsT32GM140935 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Anna Huttenlocher, Jeniel E Nett · 2021 to 2026
$6.5M
Auditory function, cognition, language and brain structure in Down Syndrome- Admin SupplementR01DC019511 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI ANDREW L ALEXANDER, Sigan L Hartley · 2022 to 2026
$3.4M
Binaural processing and hearing in children with cochlear implantsR01DC020355 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI Ruth Y Litovsky · 2023 to 2026
$2.3M
Neurobehavioral Development of Emotion Regulation in Young ChildrenK01MH113710 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI PLANALP, ELIZABETH · 2018 to 2021
$531k
3/3; Promoting resilience in children:Protocol Development for a Birth Cohort Study to Access Factors Impacting NeurodevelopmentR34DA050258 · NIDA · UNIVERSITY OF WISCONSIN-MADISON · PI ALEXANDER, ANDREW L · 2019 to 2019
$523k
NIDA NIH HHS R34 DA050258NIDCD NIH HHS R01 DC003083NIDCD NIH HHS R01 DC019511NIDCD NIH HHS R01 DC020355NIGMS NIH HHS T32 GM140935NIH HHS T32 GM140935NIMH NIH HHS K01 MH113710NIMH NIH HHS R00 MH11056
6 · The paper itself

Abstract

Inhibitory control (IC) develops in stages from infancy through adolescence and is associated with numerous developmental disorders and learning outcomes. This study examined how neural architecture - in particular myelination - underlies brain activation patterns observed during IC tasks in a sample of 28 children aged 4-10 years old. IC was observed using reaction times during go/no-go and flanker IC tasks. Myelination was measured using quantitative longitudinal relaxation rate (R1) mapping obtained from selected white matter regions of interest (ROIs). Brain activation was defined as task-related changes in hemoglobin oxygenation as measured by functional near-infrared spectroscopy (fNIRS) averaged within ROIs. Results indicated that myelination in ROIs was higher in older children and fNIRS activation in frontal channels was significantly and positively associated with go/no-go mean reaction time. Myelination in the corona radiata and superior longitudinal fasciculus was positively associated with frontal fNIRS activation, while myelination was negatively associated with go/no-go and flanker mean reaction times across white matter ROIs. Overall, significance level notably varied across models. Independently of inhibitory control constructs, these regions may be of interest in future structure-function studies across development.

Indexed as

BrainInhibition, PsychologicalBrain MappingChildChild, PreschoolFemaleHumansMagnetic Resonance ImagingMaleNeuropsychological TestsReaction TimeSpectroscopy, Near-InfraredWhite MatterBrain activationFunctional near-infrared spectroscopyInhibitory controlMagnetic resonance imagingMyelinQuantitative relaxometry

Identifiers

PMID40715851
PMCPMC12296776

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.