ArticleCommunications biology2025
Fear perception as a function of hemisphere- and time-specific dynamics in the medial temporal lobes.
Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The medial temporal lobes (mTL) are thought to enhance visual processing of fearful faces, yet the underlying mechanisms remain underspecified. To fill this gap, we recorded and compared event-related potentials (ERPs) and stimulus-induced gamma-band activity (GBA) from 36 patients with left- or right-hemispheric antero-medial temporal lobe resections including the amygdala (lTLR/rTLR) and 18 healthy controls. Only rTLR patients were found to lack fear-neutral differentiation in early P1 amplitudes (~100 ms) and exhibited heightened GBA for neutral faces over ipsi-resectional occipito-temporal areas (95-300 ms). lTLR patients showed strongest emotion differentiation in ERP components beyond the P1. Therefore, the right mTL, potentially particularly the amygdala, appears to support rapid attentional shifts toward fear and to coordinate fear-neutral differentiation in GBA. Conversely, the left mTL seems to down-regulate fear responses. These results reveal complementary, lateralized, and time-specific roles of the medial temporal lobes in fear processing, thereby refining models of emotional vision.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.