Evidence map›Paper›PMID 40715739›Full record

ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2026

First unscheduled hospitalization in advanced cancer as a prognostic indicator of poor survival and trigger for palliative care referral.

Alberto Alonso-Babarro, Juan Luis Torres-Tenor, Andrea García-Leal, Darío Sánchez-Cabrero, Lorena Ostios-García, Jesús Miranda-Poma, Laura Gutiérrez-Sainz, Julia Villamayor-Sánchez, José Abelardo Blanco-Iglesias, Javier Mateo-Flores and 2 more

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In one paragraph

Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Digital health interventions for informal cancer caregivers' mental health management: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alberto Alonso-BabarroDepartment of Palliative Care, La Paz Hospital, Paseo de la Castellana 261, 28046, Madrid, Spain.
Juan Luis Torres-TenorDepartment of Palliative Care, La Paz Hospital, Paseo de la Castellana 261, 28046, Madrid, Spain. torrestenor@yahoo.es.ORCID http://orcid.org/0009-0006-7471-1325
Andrea García-LealDepartment of Medical Oncology, La Paz Hospital, Madrid, Spain.
Darío Sánchez-CabreroDepartment of Medical Oncology, La Paz Hospital, Madrid, Spain.
Lorena Ostios-GarcíaDepartment of Medical Oncology, La Paz Hospital, Madrid, Spain.
Jesús Miranda-PomaDepartment of Medical Oncology, QuironSalud Madrid Hospital, Pozuelo de Alarcón, Spain.
Laura Gutiérrez-SainzDepartment of Medical Oncology, La Paz Hospital, Madrid, Spain.
Julia Villamayor-SánchezDepartment of Medical Oncology, La Paz Hospital, Madrid, Spain.
José Abelardo Blanco-IglesiasDepartment of Emergency Medicine, Comarcal Monforte de Lemos Hospital, Monforte de Lemos, Spain.
Javier Mateo-FloresDepartment of Palliative Care, Clínico San Carlos Hospital, Madrid, Spain.
Adriana VañóDepartment of Palliative Care, MD Anderson Cancer Center Madrid, Madrid, Spain.
Eduardo BrueraDepartment of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer, Houston, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate whether the first unscheduled hospitalization in advanced cancer may serve as a prognostic indicator of poor survival and a potential trigger for palliative care referral. METHODS/PATIENTS: Retrospective study in two tertiary hospitals using time-separated cohorts, analyzing only each patient's first unscheduled admission. Primary outcome was post-admission overall survival (OS).

resultsMedian post-admission OS was 164 days (95% CI 139-184) in the first cohort (1033 patients) and 108 days (95% CI 83-136) in the second cohort (638 patients). Male sex (p < 0.001), older age (p < 0.001), poor performance status (p < 0.001), longer admissions (p < 0.001) and tumor-related admissions (p < 0.001) were associated with lower survival in both cohorts. Previous treatment with immunotherapy (p = 0.003) or targeted therapy (p = 0.002), immunotherapy toxicity as the reason for admission (p < 0.001), and breast (p < 0.001) and gynecological (p < 0.001) cancers were associated with better survival. Cohorts showed consistent baseline characteristics and outcomes.

conclusionsIn patients with advanced cancer, the first unscheduled hospitalization may serve as a prognostic indicator of poor survival and a potential trigger for palliative care referral.

Indexed as

HospitalizationNeoplasmsPalliative CareReferral and ConsultationAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesSurvival RateAdvanced cancerHospitalizationPalliative carePalliative referralPalliative triggerPrognosis

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.