ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025
Addressing inequities in neurological mortality: trends and disparities in anoxic brain injury deaths, 1999-2023.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDespite the slowly declining prevalence of anoxic brain injury (ABI) due to newer drugs and guidelines, there still exists inequity in timely receipt of treatment. This study aims to provide a comprehensive evaluation of ABI mortality trends and sociodemographic disparities in the United States from 1999 to 2023.
methodsMortality data were obtained from the CDC-WONDER Database. The study focused on ABI-related deaths among adults aged 35 to 85 + years between 1999 and 2023. Demographic and regional variables were analyzed, including gender, race/ethnicity, age groups, census region, state, urbanization, and place of death. Average annual percentage changes (AAPC) were calculated, and trends were evaluated using the Joinpoint Regression.
resultsFrom 1999 to 2023, there were a total of 117,148 ABI-related deaths. The overall age-adjusted mortality rate (AAMR) showed a mild increase from 1999 to 2004, followed by a sharp increase until 2017, and a subsequent decline (APC: -3.10% [95% CI, -4.1% to -2.37%]. Males consistently exhibited higher mortality rates compared to females. Significant racial disparities were observed, with African Americans demonstrating higher AAMRs (7.67) than other racial groups. Both urban and rural areas experienced trends in ABI mortality, with rural areas showing higher AAMRs.
conclusionDespite recent declines in overall ABI mortality trends, significant disparities persist across demographic and geographic lines. Targeted public health interventions are necessary to address risk factors leading to ABI, particularly among high-risk groups such as racial minorities and rural populations.
Indexed as
Identifiers
40715641What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.