Evidence map›Paper›PMID 40715623›Full record

Observational studyAnnals of surgical oncology2025

Staging Laparoscopy in Gastric Cancer Patients Treated with Curative Intent: A European GASTRODATA Cohort Study.

Katarzyna Sędłak, Sebastian Kobiałka, Zuzanna Pelc, Yutaka Endo, Ines Gockel, Johanna van Sandick, Gian Luca Baiocchi, Bas Wijnhoven, Suzanne Gisbertz, Manuel Pera and 21 more

Abstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Annals of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Katarzyna SędłakDepartment of Surgical Oncology, Medical University of Lublin, Lublin, Poland. sedlak.katarz@gmail.com.ORCID http://orcid.org/0000-0003-3152-1063
Sebastian KobiałkaDepartment of Surgical Oncology, Medical University of Lublin, Lublin, Poland.
Zuzanna PelcDepartment of Surgical Oncology, Medical University of Lublin, Lublin, Poland.
Yutaka EndoDepartment of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH, USA.
Ines GockelDepartment of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of Leipzig, Leipzig, Germany.
Johanna van SandickDepartment of Surgical Oncology, The Netherlands Cancer Institute-Antoni Van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Gian Luca BaiocchiDepartment of Clinical and Experimental Sciences, Surgical Clinic, University of Brescia, and Third Division of General Surgery, Spedali Civili Di Brescia, Brescia, Italy.
Bas WijnhovenDepartment of General Surgery, Erasmus Medical Center, Rotterdam, The Netherlands.
Suzanne GisbertzDepartment of Surgery, University Medical Center Amsterdam, Amsterdam, The Netherlands.
Manuel PeraDepartment of Digestive Surgery, Hospital Universitario Del Mar, Barcelona, Spain.
Paolo MorgagniDepartment of General Surgery, Morgagni-Pierantoni Hospital, Forlì, Italy.
Massimo FramariniDepartment of General Surgery, Morgagni-Pierantoni Hospital, Forlì, Italy.
Arnulf HoelscherContilia Center for Esophageal Diseases, Elisabeth Hospital Essen, Essen, Germany.
Stefan MoenigGeneva University Hospital, Geneva, Switzerland.
Piotr KołodziejczykDepartment of Surgery, Jagiellonian University Medical College, Kraków, Poland.
Guillaume PiessenDepartment of Digestive and Oncological Surgery, University Lille, and Claude Huriez University Hospital, Lille, France.
Clarisse EvenoDepartment of Digestive and Oncological Surgery, University Lille, and Claude Huriez University Hospital, Lille, France.
Paulo Matos da CostaFaculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal.
Andrew DaviesDepartment of Upper Gastrointestinal and General Surgery, Guy's and St Thomas' Hospital, London, UK.
William AllumDepartment of Surgery, Royal Marsden NHS Foundation Trust, London, UK.
Uberto Fumagalli RomarioDigestive Surgery, European Institute of Oncology, IRCCS, Milan, Italy.
Ricardo RosatiDepartment of Gastrointestinal Surgery, IRCCS San Raffaele Hospital Research Institute, Milan, Italy.
Daniel ReimDepartment of Surgery, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.
Lucio Lara SantosExperimental Pathology and Therapeutics Group, Department of Surgical Oncology, Portuguese Institute of Oncology, Porto, Portugal.
Domenico D'ugoDepartment of General Surgery, Fondazione Policlinico Gemelli, Rome, Italy.
Giovanni De ManzoniGeneral and Upper G.I. Surgery Division, Department of Surgery, University of Verona, Verona, Italy.
Wojciech KielanDepartment of General and Oncological Surgery, Wroclaw Medical University, Wrocław, Poland.
Paul M SchneiderDigestive Oncology Tumor Center and Esophageal Cancer Center, Hirslanden Medical Center Zurich, Zurich, Switzerland.
Timothy M PawlikDepartment of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH, USA.
Wojciech PolkowskiDepartment of Surgical Oncology, Medical University of Lublin, Lublin, Poland.
Karol Rawicz-PruszyńskiDepartment of Surgical Oncology, Medical University of Lublin, Lublin, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn current guidelines, staging laparoscopy (SL) is recommended in patients with locally advanced gastric cancer (GC). This study aimed to assess the clinical practice of SL and its association with administration of systemic treatment in a European cohort of GC patients (GASTRODATA).

methodsIn this retrospective cohort study, patients with locally advanced GC who underwent multimodal treatment in 24 European centers were analyzed. Patients with early (cT1) or metastatic GC at diagnosis and those with missing data on chemotherapy administration were excluded.

resultsOf 2558 patients, 1726 were selected, with 562 (32.6%) undergoing SL. Patients who did not undergo SL were older (72 vs. 65 years; p < 0.001) and had higher Charlson Comorbidity Index scores (≥ 2: 33.8% vs. 20.5%; p < 0.001). These patients had more complications (30.9% vs. 24.4%; p = 0.005), higher 90-day mortality (4.7% vs. 2.3%; p = 0.017), and were less likely to receive neoadjuvant (35% vs. 78.6%; p < 0.001) or adjuvant (27.1% vs. 33.8%; p = 0.005) chemotherapy. Non-SL patients had higher rates of serosal invasion (pT4: 38.0% vs. 26.0%; p < 0.001) and lymph node metastasis (63.5% vs. 60.4%; p = 0.004).

conclusionsSL was performed in one-third of individuals with locally advanced GC. Absence of SL was associated with higher T-stage discrepancy and decreased utilization of multimodal treatment.

Indexed as

AdenocarcinomaAntineoplastic Combined Chemotherapy ProtocolsGastrectomyLaparoscopyStomach NeoplasmsAgedAged, 80 and overCombined Modality TherapyEuropeFemaleFollow-Up StudiesHumansLymphatic MetastasisMaleMiddle AgedNeoadjuvant TherapyGastric cancerMultimodal treatmentStaging laparoscopy

Identifiers

PMID40715623
PMCPMC12454547

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.