Evidence map›Paper›PMID 40715590›Full record

Observational studySleep & breathing = Schlaf & Atmung2025

Evaluation of sleep quality and engraftment in patients undergoing mobilization and hematopoietic stem cell transplantation.

Nur Soyer, Mehmet Sezai Tasbakan, Filiz Vural, Ozen K Basoglu

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nur SoyerDepartment of Internal Medicine, Division of Hematology, Faculty of Medicine, Ege University, Izmir, Türkiye. drakadnur@yahoo.com.ORCID 0000-0002-7722-506X
Mehmet Sezai TasbakanDepartment of Respiratory Medicine, Faculty of Medicine, Ege University, Izmir, Türkiye.ORCID 0000-0003-4507-9851
Filiz VuralDepartment of Internal Medicine, Division of Hematology, Faculty of Medicine, Ege University, Izmir, Türkiye.ORCID 0000-0003-3489-296X
Ozen K BasogluDepartment of Respiratory Medicine, Faculty of Medicine, Ege University, Izmir, Türkiye.ORCID 0000-0001-8168-6611

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate the prevalence and predictors of poor sleep quality in patients undergoing stem cell mobilization and transplantation, and to investigate the relationship between sleep quality and post-transplant engraftment.

methodsThis prospective, observational study comprised 107 patients with hematopoietic stem cell transplantation. Pittsburgh Sleep Quality Index [PSQI], Hospital Anxiety and Depression Scale [HADS] and World Health Organization Quality of Life-Brief Version [WHOQOL] questionnaires were administered before and after transplantation. Mann-Whitney and Student's t-tests were used to compare means. Logistic regression was used to analyze predictors of poor sleep quality after transplantation.

resultsOf 107 patients [mean age 53.1 ± 13.6 years; 44.9% women], 46 [43%] had poor sleep quality before transplantation. There was a significant difference between baseline and post-transplant PSQI scores [p = 0.036]. Both the PSQI scores [5.3 ± 3.4 vs. 8.0 ± 4.2, p = 0.001] and the percentage of patients with poor sleep quality [35.7% vs. 75%, p = 0.007] increased after transplantation in allogeneic patients. The presence of engraftment, PNL and PLT engraftment time were similar in good/poor sleepers at baseline, respectively [p = 0.11, p = 0.523, p = 0.341]. There was no association between sleep quality and engraftment. The risk factors affecting poor sleep quality after transplantation were PSQI score at baseline and type of transplantation in logistic regression analysis.

conclusionsThere is an increase after allogeneic transplantation in poor sleepers. The presence of engraftment and engraftment times were similar between good and poor sleepers at baseline. PSQI score at baseline and type of transplantation were risk factors for poor sleep quality after transplantation.

Indexed as

Hematopoietic Stem Cell MobilizationHematopoietic Stem Cell TransplantationSleep QualitySleep Wake DisordersAdultAgedFemaleHumansMaleMiddle AgedProspective StudiesQuality of LifeAnxietyDepressionQuality of lifeSleep qualityStem cell transplantation

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.