Evidence map›Paper›PMID 40715533›Full record

ArticleAnalytical and bioanalytical chemistry2025

Combining electroless ionisation mass spectrometry with solid-phase extraction for the direct analysis of beta-agonists in bovine urine.

Sjors Rasker, Joris Schipperheijn, Stefan Kooij, Marco H Blokland, Cees J M van Rijn, Ane Arrizabalaga-Larrañaga

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sjors RaskerWageningen Food Safety Research (WFSR), Part of Wageningen University & Research, P.O. Box 230, Wageningen, 6700 AE, the Netherlands. sjors.rasker@wur.nl.ORCID http://orcid.org/0009-0005-9177-6369
Joris SchipperheijnWageningen Food Safety Research (WFSR), Part of Wageningen University & Research, P.O. Box 230, Wageningen, 6700 AE, the Netherlands.ORCID http://orcid.org/0009-0001-2583-2925
Stefan KooijVan der Waals-Zeeman Institute, University of Amsterdam, Science Park 904, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0002-7454-6861
Marco H BloklandWageningen Food Safety Research (WFSR), Part of Wageningen University & Research, P.O. Box 230, Wageningen, 6700 AE, the Netherlands.ORCID http://orcid.org/0000-0002-3751-6065
Cees J M van RijnVan der Waals-Zeeman Institute, University of Amsterdam, Science Park 904, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0001-8380-3834
Ane Arrizabalaga-LarrañagaWageningen Food Safety Research (WFSR), Part of Wageningen University & Research, P.O. Box 230, Wageningen, 6700 AE, the Netherlands.ORCID http://orcid.org/0000-0002-9379-5775

Funding

Ministry of Agriculture, Fisheries, Food Security and Nature KB-56-002-007
6 · The paper itself

Abstract

A novel method combining electroless ionisation mass spectrometry (ELI-MS) with solid-phase extraction (SPE) cartridges enables direct analysis of beta-agonist residues in bovine urine (SPE-ELI-MS). Using a syringe plunger and a battery-powered DIY syringe pump mounted on an XYZ-linear stage, rapid sample clean-up and precise positioning were achieved. Optimisation of spray solvent and nozzle placement improved performance, yielding high sensitivity, repeatability, linearity, and trueness with internal standard correction. This approach offers a simple, efficient solution for analysing organic residues in biological samples, with strong potential for future on-site applications.

Indexed as

Adrenergic beta-AgonistsMass SpectrometrySolid Phase ExtractionAnimalsCattleLimit of DetectionReproducibility of ResultsAdrenergic beta-AgonistsAmbient ionisation mass spectrometryBeta-agonistsBovine urineElectroless ionisationELI-MSSolid-phase extraction

Identifiers

PMID40715533
PMCPMC12402018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.