Evidence map›Paper›PMID 40715531›Full record

ArticleCommunications engineering2025

Design and application of a realistic and multifunctional retinal phantom for standardizing ophthalmic imaging systems.

Hyun-Ji Lee, Tae Geol Lee, Il Doh, Sang-Won Lee

Abstract read
In one paragraph

Article in Communications engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hyun-Ji LeeNanobio Measurement Group, Korea Research, Institute of Standards and Science, Daejeon, Republic of Korea.
Tae Geol LeeNanobio Measurement Group, Korea Research, Institute of Standards and Science, Daejeon, Republic of Korea.
Il DohMedical Metrology Group, Korea Research, Institute of Standards and Science, Daejeon, Republic of Korea. il.doh@kriss.re.kr.ORCID http://orcid.org/0000-0002-1639-7730
Sang-Won LeeNanobio Measurement Group, Korea Research, Institute of Standards and Science, Daejeon, Republic of Korea. swlee76@kriss.re.kr.ORCID http://orcid.org/0000-0001-6952-6957

Funding

Korea Research Institute of Standards and Science (KRISS) KRISS-GP2025-0007-02Korea Research Institute of Standards and Science (KRISS) KRISS-GP2025-0007-03National Research Council of Science and Technology (National Research Council of Science & Technology) CRC24021-000
6 · The paper itself

Abstract

Retinal imaging is essential for diagnosing and treating retinal diseases. However, the lack of standardized and realistic optical phantoms limits the calibration and validation of imaging systems. Here we developed a realistic retinal phantom based on the concept of a super phantom designed to replicate the morphological and functional characteristics of the human retina. The phantom comprises a 13-layered structure, microfluidic channels to emulate vascular networks in the human retina, and fluorescent microbeads to replicate retinal autofluorescence. We validated the measurement of axial resolution, depth range, and field-of-view of optical coherence tomography (OCT) using the phantom. In addition, we confirmed the utility of the phantom across multiple ophthalmic imaging modalities, including OCT, OCT angiography, fundus autofluorescence, fluorescein angiography, and indocyanine green angiography. Imaging systems will be able to enhance the diagnosis and therapeutic monitoring of retinal diseases by standardizing imaging systems with this phantom and improving both the qualitative analysis and the accuracy of quantitative parameters, such as retinal thickness.

Identifiers

PMID40715531
PMCPMC12297689

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.