Evidence map›Paper›PMID 40715524›Full record

ArticleScientific reports2025

Astral-based DIA proteomics analysis reveals the effects of selenium on Pleurotus pulmonarius.

Chengxuan Xu, Lijuan Qian, Qi Meng, Xiangru Meng, Yujun Sun

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chengxuan Xu *College of Agriculture, Anhui Science and Technology University, Fengyang, 233100, China.
Lijuan Qian *College of Agriculture, Anhui Science and Technology University, Fengyang, 233100, China.
Qi MengCollege of Biomedicine and Health, Anhui Science and Technology University, Fengyang, 233100, China.
Xiangru MengCollege of Agriculture, Anhui Science and Technology University, Fengyang, 233100, China.
Yujun SunCollege of Biomedicine and Health, Anhui Science and Technology University, Fengyang, 233100, China. Sunyj@ahstu.edu.cn.

Funding

Yujun Sun KJ2021ZD0107
6 · The paper itself

Abstract

This study investigates the effects of sodium selenite on the yield, selenium content, and proteomic profile of Pleurotus pulmonarius (P. pulmonarius). Treatment with 2 µg/mL sodium selenite (PP-Se2) resulted in a 17.87% increase in the yield of P. pulmonarius. In contrast, treatment with 10 µg/mL sodium selenate (PP-Se10) caused a 23.58% reduction in yield. The selenium content exhibited a positive correlation with the sodium selenite concentration in the cultivation substrate. Based on data-independent acquisition (DIA) proteomics analysis, it was revealed that PP-Se2 and PP-Se10 contained 141 differential expressed proteins (DEPs) (64 up-regulated and 77 down-regulated) and 129 DEPs (73 up-regulated and 56 down-regulated), respectively. DEPs in PP-Se2 were predominantly involved in carbon metabolism, ribosomes, peroxisomes, and ABC transporters. In contrast, DEPs in PP-Se10 were primarily enriched in the biosynthesis of secondary metabolites and cysteine and methionine metabolism. These results suggest that P. pulmonarius exhibits distinct metabolic response mechanisms to varying levels of selenium treatment, with these pathways potentially being influenced by selenium concentration. These findings help to fill the gap in selenium proteomics research in edible fungi and provide new theoretical insights for the development of selenium-enriched functional foods.

Indexed as

Fungal ProteinsPleurotusProteomeProteomicsSeleniumSodium SeleniteGene Expression Regulation, FungalFungal ProteinsProteomeSeleniumSodium SeleniteMolecular reactionPleurotus pulmonariusProteomicsSelenium stressSodium selenite

Identifiers

PMID40715524
PMCPMC12297576

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.