Evidence map›Paper›PMID 40715446›Full record

ArticleScientific reports2025

Biosynthesis of selenium nanoparticles from Dahlia pinnata tuberous roots with antibacterial, antidiabetic, and erythrocyte membrane protective activities.

Alsayed E Mekky, Abdullah M Abdo, Muhammed I Haggag, Mohammed H Elhaw, Mostafa M Kadry, Sameh M Ghanem, Mokhtar M Salama, Amal M Soliman, Nashaat N Mahmoud

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alsayed E MekkyBotany and Microbiology Department, Faculty of Science, Al-Azhar University, P.O. Box 11884, Nasr City, Cairo, Egypt.
Abdullah M AbdoBotany and Microbiology Department, Faculty of Science, Al-Azhar University, P.O. Box 11884, Nasr City, Cairo, Egypt. abdullah.abdo@azhar.edu.eg.ORCID http://orcid.org/0000-0003-0087-0674
Muhammed I HaggagBotany and Microbiology Department, Faculty of Science, Al-Azhar University, P.O. Box 11884, Nasr City, Cairo, Egypt.
Mohammed H ElhawBotany and Microbiology Department, Faculty of Science, Al-Azhar University, P.O. Box 11884, Nasr City, Cairo, Egypt.
Mostafa M KadryFood Science and Technology Department, Faculty of Agriculture, Al-Azhar University, P.O. Box 13759, Nasr City, Cairo, Egypt.
Sameh M GhanemFood Science and Technology Department, Faculty of Agriculture, Al-Azhar University, P.O. Box 13759, Nasr City, Cairo, Egypt.
Mokhtar M SalamaFood Science and Technology Department, Faculty of Agriculture, Al-Azhar University, P.O. Box 13759, Nasr City, Cairo, Egypt.
Amal M SolimanDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Ain-Shams University, P.O. Box 1181, Cairo, Egypt.
Nashaat N MahmoudBotany and Microbiology Department, Faculty of Science, Al-Azhar University, P.O. Box 11884, Nasr City, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selenium nanoparticles (SeNPs) synthesized using Dahlia pinnata L tuber extract exhibit significant antimicrobial, antidiabetic, and anti-inflammatory properties. This study describes the green synthesis of SeNPs using D. pinnata L. tuber extract, a sustainable approach that leverages plant-based compounds. Green synthesis was confirmed via UV-Vis spectroscopy (280 nm peak), XRD trigonal crystal structure with planes (100), (101), (110), (111), and (201), and TEM (spherical particles, 17.37 nm average size). FTIR revealed functional groups (C-H, C = O, Se-Se), while HPLC identified gallic acid (1070.58 µg/g) and chlorogenic acid (903.87 µg/g). In antimicrobial studies, SeNPs demonstrated strong efficacy against 70 Escherichia coli isolates from laboratory samples of diabetic patients. For 15 multidrug-resistant (MDR, 21.4%) isolates, SeNPs had MICs of 25-50 µg/ml (mean: 35 ± 12 µg/ml) and MBCs of 50-100 µg/ml (mean: 76.6 ± 26 µg/ml). Non-MDR isolates (78.6%) were more sensitive, with MICs of 10-25 µg/ml (mean: 15 ± 4.5 µg/ml) and MBCs of 25-50 µg/ml (mean: 35 ± 12 µg/ml), outperforming selenium precursors and vancomycin. SeNPs also showed antidiabetic potential through α-amylase inhibition (IC

Indexed as

Anti-Bacterial AgentsErythrocyte MembraneHypoglycemic AgentsMetal NanoparticlesNanoparticlesPlant RootsSeleniumEscherichia coliHumansMicrobial Sensitivity TestsPlant ExtractsAnti-Bacterial AgentsHypoglycemic AgentsPlant ExtractsSeleniumAntidiabetic potentialAntimicrobial activityDahlia pinnata L.Escherichia coliGreen synthesisSelenium nanoparticles (SeNPs)

Identifiers

PMID40715446
PMCPMC12297624

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.