Evidence map›Paper›PMID 40715356›Full record

ArticleScientific reports2025

Automated characterization of abdominal MRI exams using deep learning.

Joonghyun Kim, Allison Chae, Jeffrey Duda, Arijitt Borthakur, Daniel J Rader, James C Gee, Charles E Kahn, Penn Medicine BioBank, Walter R Witschey, Hersh Sagreiya

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Joonghyun KimDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA. brianjkim0209@gmail.com.
Allison ChaeDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jeffrey DudaDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Arijitt BorthakurDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Daniel J RaderDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
James C GeeDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Charles E KahnDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Penn Medicine BioBank
Walter R WitscheyDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Hersh SagreiyaDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Hersh.Sagreiya@pennmedicine.upenn.edu.

Funding

Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
High Spatial and Temporal Resolution MRI Mapping of Oxygen Consumption in HumansP41EB029460 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Ravinder Reddy · 2021 to 2026
$7.6M
Cardiac MR imaging of hemorrhagic reperfusion injury after myocardial infarctionR01HL137984 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI WITSCHEY, WALTER R.T. · 2018 to 2022
$2.8M
Advanced Normalization ToolsR01EB031722 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI GEE, JAMES C · 2022 to 2025
$2.7M
ITK-Lung: A Software Framework for Lung Image Processing and AnalysisR01HL133889 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI GEE, JAMES C · 2017 to 2020
$2.3M
NCATS NIH HHS UL1 TR001878NCATS NIH HHS UL1TR001878NHLBI NIH HHS R01 HL133889NHLBI NIH HHS R01-HL133889NHLBI NIH HHS R01 HL137984NIBIB NIH HHS P41 EB029460NIBIB NIH HHS R01 EB031722NIBIB NIH HHS R01-EB031722NIH HHS HL137984Radiological Society of North America RSCH2028
6 · The paper itself

Abstract

Advances in magnetic resonance imaging (MRI) have revolutionized disease detection and treatment planning. However, the growing volume and complexity of MRI data-along with heterogeneity in imaging protocols, scanner technology, and labeling practices-creates a need for standardized tools to automatically identify and characterize key imaging attributes. Such tools are essential for large-scale, multi-institutional studies that rely on harmonized data to train robust machine learning models. In this study, we developed convolutional neural networks (CNNs) to automatically classify three core attributes of abdominal MRI: pulse sequence type, imaging orientation, and contrast enhancement status. Three distinct CNNs with similar backbone architectures were trained to classify single image slices into one of 12 pulse sequences, 4 orientations, or 2 contrast classes. The models achieved high classification accuracies of 99.51%, 99.87%, and 99.99% for pulse sequence, orientation, and contrast, respectively. We applied Grad-CAM to visualize image regions influencing pulse sequence predictions and highlight relevant anatomical features. To enhance performance, we implemented a majority voting approach to aggregate slice-level predictions, achieving 100% accuracy at the volume level for all tasks. External validation using the Duke Liver Dataset demonstrated strong generalizability; after adjusting for class label mismatch, volume-level accuracies exceeded 96.9% across all classification tasks.

Indexed as

AbdomenDeep LearningImage Processing, Computer-AssistedMagnetic Resonance ImagingHumansNeural Networks, Computer

Identifiers

PMID40715356
PMCPMC12297695

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.