Evidence map›Paper›PMID 40715123›Full record

ArticleNature communications2025

OsBZR4 regulates temperature-dependent embryogenesis in rice.

Zhenyu Wang, Min Xu, Yingxiang Liu, Xiaoming Zheng, Zhipeng Hong, Mingliang He, Xin Jin, Jiaqi Tang, Xiufeng Li, Xiaojie Tian and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhenyu Wang *Northeast Institute of Geography and Agroecology, State Key Laboratory of Black Soils Conservation and Utilization, Key Laboratory of Soybean Molecular Design Breeding, Chinese Academy of Sciences, Harbin, China.
Min Xu *Northeast Institute of Geography and Agroecology, State Key Laboratory of Black Soils Conservation and Utilization, Key Laboratory of Soybean Molecular Design Breeding, Chinese Academy of Sciences, Harbin, China.
Yingxiang LiuNortheast Institute of Geography and Agroecology, State Key Laboratory of Black Soils Conservation and Utilization, Key Laboratory of Soybean Molecular Design Breeding, Chinese Academy of Sciences, Harbin, China.
Xiaoming ZhengNational Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Zhipeng HongNortheast Institute of Geography and Agroecology, State Key Laboratory of Black Soils Conservation and Utilization, Key Laboratory of Soybean Molecular Design Breeding, Chinese Academy of Sciences, Harbin, China.
Mingliang HeNortheast Institute of Geography and Agroecology, State Key Laboratory of Black Soils Conservation and Utilization, Key Laboratory of Soybean Molecular Design Breeding, Chinese Academy of Sciences, Harbin, China.
Xin JinNortheast Institute of Geography and Agroecology, State Key Laboratory of Black Soils Conservation and Utilization, Key Laboratory of Soybean Molecular Design Breeding, Chinese Academy of Sciences, Harbin, China.
Jiaqi TangNortheast Institute of Geography and Agroecology, State Key Laboratory of Black Soils Conservation and Utilization, Key Laboratory of Soybean Molecular Design Breeding, Chinese Academy of Sciences, Harbin, China.
Xiufeng LiNortheast Institute of Geography and Agroecology, State Key Laboratory of Black Soils Conservation and Utilization, Key Laboratory of Soybean Molecular Design Breeding, Chinese Academy of Sciences, Harbin, China.
Xiaojie TianNortheast Institute of Geography and Agroecology, State Key Laboratory of Black Soils Conservation and Utilization, Key Laboratory of Soybean Molecular Design Breeding, Chinese Academy of Sciences, Harbin, China.
Qian QianYazhouwan Laboratory, Sanya, China. qianqian188@hotmail.com.ORCID http://orcid.org/0000-0002-0349-4937
Qingyun BuNortheast Institute of Geography and Agroecology, State Key Laboratory of Black Soils Conservation and Utilization, Key Laboratory of Soybean Molecular Design Breeding, Chinese Academy of Sciences, Harbin, China. buqingyun@iga.ac.cn.ORCID http://orcid.org/0000-0002-5386-3577

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32171988National Natural Science Foundation of China (National Science Foundation of China) 32171989National Natural Science Foundation of China (National Science Foundation of China) U23A20193
6 · The paper itself

Abstract

Embryoless rice is valuable for studying early seed development and has great breeding potential, however, related research remains limited. Here, we show that mutations in OsBZR4, encoding brassinazole-resistance 4, lead to 60-100% embryoless seeds across different cultivars. OsBZR4 is specifically expressed at the scutellum-endosperm interface and regulates auxin levels and distribution during early embryo development. OsBZR4 represses the expression of YUC4 and PIN5b. Exogenous auxin and overexpression of YUC4 enhance the embryoless ratio, whereas the auxin transport inhibitor N-1-naphthylphthalamic acid (NPA) decrease it. Higher temperatures increase the embryoless ratio in bzr4 mutant lines. The expression of OsPIL13 is induced by high temperature, and its overexpression enhances the embryoless ratio in both wild type and bzr4 plants. Introducing bzr4 mutant allele into some elite cultivars can improve milled rice yield and storability. Collectively, manipulating OsBZR4 can lead to the development of thermosensitive embryoless rice varieties with increased energy reserves and improved storability, potentially enabling novel rice production technologies.

Indexed as

OryzaPlant ProteinsSeedsGene Expression Regulation, DevelopmentalGene Expression Regulation, PlantIndoleacetic AcidsMutationPhthalimidesPlants, Genetically ModifiedTemperatureIndoleacetic AcidsPhthalimidesPlant Proteins

Identifiers

PMID40715123
PMCPMC12296736

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.