Evidence map›Paper›PMID 40715053›Full record

ArticleBDJ open2025

Clinical and radiographic outcomes after pulpotomies using mineral trioxide aggregate mixed with distilled water or 2.25% sodium hypochlorite gel: a randomized controlled clinical trial.

Mawia Karkoutly, Amjad Abu Hasna, Ok Hyung Nam, Ricardo Machado, Saleh Al Kurdi, Nada Bshara

Abstract read
In one paragraph

Article in BDJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mawia KarkoutlyDepartment of Pediatric Dentistry, Faculty of Dentistry, Damascus University, Damascus, Syrian Arab Republic. mawia95.karkoutly@damascusuniversity.edu.sy.ORCID http://orcid.org/0000-0003-0227-1560
Amjad Abu HasnaDepartment of Restorative Dentistry, Endodontics Division, Institute of Science and Technology, São Paulo State University (ICT-UNESP) Eng. Francisco José Longo Avenue 777, São José dos Campos, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-1112-985X
Ok Hyung NamDepartment of Pediatric Dentistry, School of Dentistry, Kyung Hee University, Seoul, Korea.
Ricardo MachadoDepartment of Restorative Sciences, Division of Endodontics, College of Dentistry, Health Sciences Center, University of Oklahoma, Oklahoma City, OK, USA.
Saleh Al KurdiDepartment of Orthodontics and Pediatric Dentistry, Faculty of Dentistry, Arab International University, Daraa, Syrian Arab Republic.
Nada BsharaDepartment of Pediatric Dentistry, Faculty of Dentistry, Damascus University, Damascus, Syrian Arab Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesSodium hypochlorite (NaOCl) gel is an effective additive for white mineral trioxide aggregate (WMTA) that enhances its chemical and physical characteristics and significantly reduces setting time while maintaining biocompatibility. The study sought to compare the outcomes of pulpotomies performed in primary teeth using WMTA mixed with 2.25% NaOCl gel or WMTA mixed with distilled water (DW). MATERIALS AND

methodsIt was a randomized, triple-blinded, split-mouth, controlled clinical trial. Forty primary second molars from cooperative children aged 5-10 who required pulpotomy were randomly assigned to the control group-WMTA  + DW or experimental group-WMTA + NaOCl gel for clinical and radiographic assessments at 3, 6, and 12 months of follow-up. The clinical evaluation involved checking for spontaneous pain, pain on percussion, tooth mobility, abscesses, sinus tracts, and the exfoliation of the treated tooth. The periapical radiographic evaluation identified whether there was furcal radiolucency, internal or external root resorption, and widening of the periodontal ligament. Canal obliteration was not considered a failure.

resultsThe WMTA + NaOCl gel group showed a 90% and 95% clinical and radiographical success rate, respectively, at 3, 6, and 12 months of follow-up. In the control group, the clinical success rate was 90% after 3, 6, and 12 months, whereas the radiographical success rate was 100% at 3 months and decreased to 95% after 6 and to 85% after 12 months. No statistically significant difference was detected between the two groups (p > 0.05).

conclusionsThe present research validated WMTA + NaOCl gel as a potentially effective material for pulpotomy in primary molars.

Identifiers

PMID40715053
PMCPMC12297548

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.