Evidence map›Paper›PMID 40715015›Full record

ArticlePhysiological reports2025

Relationship among nephron number, cortical volume, and glomerular pressure in healthy kidney donors.

Hiroki Nobayashi, Go Kanzaki, Takaya Sasaki, Rina Oba, Yusuke Okabayashi, Kotaro Haruhara, Kentaro Koike, Akimitsu Kobayashi, Izumi Yamamoto, Nobuo Tsuboi and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Are noninvasive measurements of nephron number achievable in humans?Current opinion in nephrology and hypertension · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hiroki NobayashiDivision of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.ORCID 0000-0002-1783-8024
Go KanzakiDivision of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.ORCID 0000-0002-7795-369X
Takaya SasakiDivision of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.
Rina ObaDivision of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.ORCID 0000-0001-8113-9511
Yusuke OkabayashiDivision of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.
Kotaro HaruharaDivision of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.
Kentaro KoikeDivision of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.
Akimitsu KobayashiDivision of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.
Izumi YamamotoDivision of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.
Nobuo TsuboiDivision of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.
Takashi YokooDivision of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.

Funding

the Japan Society for the Promotion of Science (JSPS) through the Grants-in-Aid for Scientific Research (KAKENHI) JP18K15987the Japan Society for the Promotion of Science (JSPS) through the Grants-in-Aid for Scientific Research (KAKENHI) JP21K16197
6 · The paper itself

Abstract

Glomerular hypertension is a critical factor in kidney disease progression. Traditionally, nephron number (Nglom) was considered a determinant of glomerular hemodynamics, but emerging evidence suggests a more substantial impact of renal structural factors. This cross-sectional study aimed to evaluate the relationship between renal histopathological parameters and intraglomerular hydrostatic pressure (Pglo) in healthy donors. Retrospective analyses were conducted on 60 healthy living donors who donated a kidney between January 1, 2007, and September 30, 2022. The non-sclerotic glomerular number (Nglom

Indexed as

Kidney CortexKidney GlomerulusNephronsAdultCross-Sectional StudiesFemaleHumansLiving DonorsMaleMiddle AgedOrgan SizeRetrospective Studiesfiltrationhemodynamicskidneynephrontubule

Identifiers

PMID40715015
PMCPMC12679943

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.