Trial reportAustralian endodontic journal : the journal of the Australian Society of Endodontology Inc2025
Evaluation of Post-Endodontic Pain Reduction Using Intracanal Cryotherapy in Symptomatic Apical Periodontitis.
Trial report in Australian endodontic journal : the journal of the Australian Society of Endodontology Inc, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This prospective experimental study evaluated the efficacy of intracanal cryotherapy in reducing postoperative pain in patients with symptomatic apical periodontitis. Ninety participants with necrotic pulp and preoperative pain (VAS ≥ 7) were randomised into two groups: Group A received room-temperature saline irrigation, while Group B received cryotreated saline (2.5°C) as the final irrigant. Pain was assessed preoperatively, at 24 h, and 48 h post-treatment using the Visual Analogue Scale. Results demonstrated significantly lower pain scores in the cryotherapy group at 24 h (p = 0.010) and 48 h (p < 0.001), with reduced analgesic use. Cryotherapy effectively mitigates post-operative pain in symptomatic apical periodontitis, offering a non-invasive adjunct to standard endodontic therapy.
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Registered trials
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