Evidence map›Paper›PMID 40714922›Full record

ArticleOral diseases2026

Endometriosis-Associated Periodontal Disease: A Large Cohort Perspective Study.

Maria Teresa Agneta, Giuseppe D'Albis, Letizia Lorusso, Nicola Bartolomeo, Antonia Abbinante, Anna Antonacci, Pietro Signorile, Francesco D'Aiuto, Elisa Mazza, Massimo Corsalini and 1 more

Abstract read
In one paragraph

Article in Oral diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maria Teresa AgnetaItalian Association of Dental Hygienists (AIDI), Bari, Italy.
Giuseppe D'AlbisInterdisciplinary Department of Medicine, Department of Dentistry, University of Bari Aldo Moro, Bari, Italy.ORCID https://orcid.org/0000-0002-3577-3711
Letizia LorussoInterdisciplinary Department of Medicine, School of Medical Statistics and Biometry, University of Bari Aldo Moro, Bari, Italy.
Nicola BartolomeoInterdisciplinary Department of Medicine, Department of Dentistry, University of Bari Aldo Moro, Bari, Italy.ORCID https://orcid.org/0000-0002-8540-4615
Antonia AbbinanteItalian Association of Dental Hygienists (AIDI), Bari, Italy.
Anna AntonacciItalian Association of Dental Hygienists (AIDI), Bari, Italy.
Pietro SignorilePresident of the Italian Endometriosis Foundation, Rome, Italy.
Francesco D'AiutoPeriodontology Unit, UCL Eastman Dental Institute, London, UK.ORCID https://orcid.org/0000-0001-8654-935X
Elisa MazzaDepartment of Clinical and Experimental Medicina, University Magna Græcia, Catanzaro, Italy.
Massimo CorsaliniInterdisciplinary Department of Medicine, Department of Dentistry, University of Bari Aldo Moro, Bari, Italy.
Saverio CapodiferroInterdisciplinary Department of Medicine, Department of Dentistry, University of Bari Aldo Moro, Bari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEndometriosis is a chronic estrogen-dependent gynecological disease affecting millions of women worldwide. Besides its well-established impact on reproductive health, emerging evidence suggests a potential association between endometriosis and periodontal disease. The present study discusses the interplay between the two diseases, exploring shared immunopathological mechanisms, including chronic inflammation, hormonal imbalance, and immune system modulation. MATERIALS AND

methodsA 45-question standardized questionnaire was answered by 4072 women clinically diagnosed with endometriosis to identify self-reported periodontal status, oral hygiene habits, and systemic symptoms.

resultsFindings report that more severe stages of endometriosis are related to increased awareness of periodontal disease, greater gingival bleeding, xerostomia, and mucosal alterations. Moreover, greater diagnostic latency aggravates both systemic and oral disorders, supporting the necessity of early treatment. These findings highlight the need for a single, multidisciplinary standard of patient care involving gynecologists, dentists, dental hygienists, and other healthcare providers.

conclusionBy connecting gynecological and dental care, this study aims to promote awareness, facilitate early diagnosis, and improve quality of life for women suffering from endometriosis. Future research must explore mechanisms linking the conditions and assess therapeutic approaches to alleviate oral health issues in these individuals.

Indexed as

EndometriosisPeriodontal DiseasesAdultCohort StudiesFemaleHumansMiddle AgedOral HygieneSurveys and QuestionnairesYoung Adultchronic inflammationendometriosismultidisciplinary careoral‐systemic connectionperiodontal disease

Identifiers

PMID40714922
PMCPMC13031406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.