ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025
A Wearable Electrochemical Biosensor for Salivary Detection of Periodontal Inflammation Biomarkers: Molecularly Imprinted Polymer Sensor with Deep Learning Integration.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Molecularly Imprinted Polymers for Biosensing: From Synthetic Recognition to Integrated Biointerfaces.Micromachines · 2026Review
- From Reactive to Proactive Healthcare: Synergizing Wearable Biomarkers and Machine Learning in Digital Therapeutics.Bioengineering (Basel, Switzerland) · 2026Review
- Advances and Challenges in Wearable Sensors for Health Monitoring.ACS applied materials & interfaces · 2026Review
- Regulating the Nano-Bio Interface: Converging Electrochemical and Photonic Biosensing for Wearable Diagnostics.Nano letters · 2026Review
- Extraoral Detection of Biomarkers and Pathogens in Saliva: Comprehensive, Panoramic Review.Biosensors · 2026Review
- AI-Assisted Molecular Biosensors: Design Strategies for Wearable and Real-Time Monitoring.International journal of molecular sciences · 2026Review
- Current Status and Future Perspectives of Wearable Technologies for Oral Health in Clinical Applications.Diagnostics (Basel, Switzerland) · 2026Review
- Advanced Diagnostic Technologies and Molecular Biomarkers in Periodontitis: Systemic Health Implications and Translational Perspectives.Journal of clinical medicine · 2026Review
- Dimensionally Engineered Nanotherapeutics for Pulpitis and Periodontitis: From Structural Design to Artificial Intelligence-Enabled Precision Therapy.International journal of nanomedicine · 2026Review
- Article
- A Wearable Electrochemical Biosensor for Salivary Detection of Periodontal Inflammation Biomarkers: Molecularly Imprinted Polymer Sensor with Deep Learning Integration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
The work presented here introduces a developed electrochemical biosensor for the salivary detection of matrix metalloproteinase-8 (MMP-8), utilizing a molecularly imprinted polymer (MIP) matrix based on poly(o-phenylenediamine). To enhance detection sensitivity and modulate impedance responses, graphene oxide (GO) is incorporated as an interlayer, providing a conductive and chemically stable matrix for precise electrochemical sensing. Density functional theory simulations confirm the formation of highly selective binding sites, further reinforcing the sensor's specificity for MMP-8 detection. The impedance-based mechanism allows real-time, label-free detection of salivary MMP-8 by tracking charge transfer resistance changes via the K[Fe(CN)₆]
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.