Evidence map›Paper›PMID 40714818›Full record

SynthesisInterdisciplinary cardiovascular and thoracic surgery2025

Surgical Ablation by a Right Mini-thoracotomy Versus a Median Sternotomy: A Systematic Review and Meta-analysis of Observational Studies.

Leo Consoli, Francisco Javier Nino Gonzalez, Henri Bartolozzi, Namira Mohammed Ali, Oluwaseun Fagbamila, Massimo Baudo

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Interdisciplinary cardiovascular and thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Leo ConsoliFaculty of Medicine, Federal University of Bahia, Salvador, 40140330, Brazil.ORCID 0000-0001-6954-6114
Francisco Javier Nino GonzalezUniversity of Deusto, School of Medicine, Bilbao, 48007, Spain.ORCID 0000-0003-0055-1411
Henri BartolozziTrakia University, School of Medicine, Stara Zagora, 6000, Bulgaria.ORCID 0009-0009-0734-5849
Namira Mohammed AliSEGi University, School of Medicine, Selangor, 47810, Malaysia.
Oluwaseun FagbamilaSaint James School of Medicine, Faculty of Medicine, Arnos Vale, 2640, Saint Vincent and the Grenadines.ORCID 0009-0005-4406-4262
Massimo BaudoDepartment of Cardiac Surgery Research, Lankenau Institute for Medical Research, Main Line Health, Wynnewood, PA, 19096, United States.ORCID 0000-0003-3754-6704

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesA minimally invasive approach by a right mini-thoracotomy has been developed for surgical ablation of atrial fibrillation. However, the efficacy and safety compared to a median sternotomy remains unclear.

methodsWe searched PubMed, Embase, and the Cochrane Library for eligible studies. Meta-analysis was performed for primary (recurrence of atrial tachyarrhythmias at 1 and 2 years) and secondary (hospital and ICU stay, adverse events, 30-day mortality, cardiopulmonary bypass, and aortic cross-clamp time) end-points. We compared end-points using risk ratio (RR) for binary outcomes and mean difference (MD) for continuous ones. We calculated 95% confidence intervals (CI) and used the random-effects model for all outcomes. We performed subgroup analysis for the main outcome based on lesion set, energy source, type of surgery, and propensity score matching.

resultsWe included 12 observational studies (n = 3122). No difference was found for the primary outcome at 1 (RR 0.8; [95% CI]: 0.62-1.03; P = 0.08) and 2 years (RR 0.9; [95% CI]: 0.74-1.13; P = 0.4). The thoracotomy group had lower complications (RR 0.72; [95% CI]: 0.55-0.97; P = 0.016), 30-day mortality (OR 0.26; [95% CI]: 0.10-0.70; P = 0.007), hospital stay (MD -5.35; [95% CI]: -7.94 to 2.77; P < 0.001), and ICU stay (MD -2.21; [95% CI]: -3.02 to 1.40; P < 0.001). Cardiopulmonary bypass and aortic clamping time were significantly higher in the thoracotomy group.

conclusionsThis meta-analysis found that surgical ablation by a mini-thoracotomy might achieve similar rhythm control to a median sternotomy while possibly improving safety and promoting faster recovery. However, conclusions are limited by the observational nature of the evidence and randomized trials are warranted.

Indexed as

Atrial FibrillationCatheter AblationSternotomyThoracotomyFemaleHumansMaleObservational Studies as TopicPostoperative ComplicationsRecurrenceRisk FactorsTime FactorsTreatment Outcomearrhythmia surgeryatrial fibrillationminimally invasive surgerysurgical ablation

Identifiers

PMID40714818
PMCPMC12343086

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.