ReviewSmall (Weinheim an der Bergstrasse, Germany)2025
Cyclodextrin-Based Pseudocopolymers and Their Biomedical Applications for Drug and Gene Delivery.
Review in Small (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Metal-Free Ternary-Composite Aerogel Based on Graphitic Carbon Nitride, Graphene Oxide, and β-Cyclodextrin for Synergistic Adsorption and Photodegradation of Organic Dyes.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Injectable Thermosensitive Hydrogel Targeting STAT3 Reprograms Neutrophils to Amplify Anti-Tumor Immunity Post-Radiofrequency Ablation in HCC.Advanced healthcare materials · 2026Article
- Smart responsive hydrogels combined with AI design for tumor therapy.Acta pharmaceutica Sinica. B · 2026Review
- Intelligent Thermo-Self-Limited Magnetothermia with Heat-Triggered TERT Silencing for Precision Synergetic Cancer Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Cyclodextrins as Modulators of Regulated Cell Death: Implications for Immunometabolism and Therapeutic Innovation.Pharmaceutics · 2026Review
- Ligand-modified multifunctional liposome-based targeted delivery platform: a multimodal cancer combination therapy strategy.Theranostics · 2026Review
- Cyclodextrin-Based Pseudocopolymers and Their Biomedical Applications for Drug and Gene Delivery.Small (Weinheim an der Bergstrasse, Germany) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Cyclodextrin (CD)-based pseudocopolymers draw on the host-guest inclusion complex properties of CDs, particularly β-CD, to form noncovalent connections with compatible guest molecules. This approach enhances the structural versatility and biocompatibility of the resulting polymer blocks. Host-guest chemistry enables the assembly of sophisticated architectures, such as comb-like grafts, star structures, and dendrimer-like forms, which are engineered for targeted, stimuli-responsive, and sustained drug release. Several innovative systems, including pH-sensitive micelles, redox-responsive nanoparticles, and dual-responsive hydrogels that provide high drug-loading capacity, controlled release, and tumor-targeted delivery, are discussed. Applications in drug and gene therapy are highlighted, where CD-based pseudocopolymers increase drug loading and transfection efficiency, reduce cytotoxicity, and facilitate the precise delivery of therapeutic agents, such as DNA and small interfering RNA. This review showcases the potential of CD-based pseudocopolymers as adaptable platforms for advanced drug and gene delivery, addressing numerous challenges posed by biological barriers, multidrug resistance, and the need for targeted therapies through rational system design. Future directions emphasize optimizing these systems for clinical translation, focusing on refining synthetic methodologies, enhancing molecular modularity, and achieving a deeper understanding of their biological compatibility.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.