ArticleAdvanced healthcare materials2025
A Deployable 4D Printed, Mucoadhesive and Magnetically Guided Patch for Local Therapy of Gastric Cancer.
Article in Advanced healthcare materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Exploring the role of 4D printing materials, techniques, and characteristics for personalized oncology.Translational oncology · 2026Review
- A Deployable 4D Printed, Mucoadhesive and Magnetically Guided Patch for Local Therapy of Gastric Cancer.Advanced healthcare materials · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
A new perspective for treatment of gastric cancer utilizing a four-dimensional (4D) printed design for deployable and magnetically guided local drug releasing patches is proposed. The deployed patches are envisioned to adhere at the tumor site in order to locally deliver high drug amounts to the tissue. The approach is considered as a platform for a gastric patch design that is flexible with reference to size and shape, active pharmaceutical ingredient (API) and dosages as well as providing unidirectional drug release. Agarose is employed as main component for the patch for its water-actuated shape transformation (curling-shrinkage/deployment) capabilities. This patch can be compactly deformed upon drying for easy ingestion. The patch is envisioned to rehydrate and expand in the stomach. In order to promote mucoadhesion, agarose hydrogel is modified with chitosan and included SPIONs to allow for magnetic guidance. The study focuses on the design and fabrication process, physicochemical characterization, and magnetization evaluation of the composite hydrogel. The hydrogel is used as an ink for 3D printing and processed into a patch loaded with a model drug. By leveraging the combination of 4D printing, magnetic guidance, and localized drug delivery, this patch has the potential to improve the effectiveness of stomach cancer treatments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.