Evidence map›Paper›PMID 40713938›Full record

ArticleProtein science : a publication of the Protein Society2025

Exploration of the interaction between dynein intermediate chain and dynactin p150

A J Di Nicola, Bryn L Romig, Stella M Davis, Paul H Cleary, Claire H Yung, Daniel R Marsan, Anna C Merkt, Nikolaus M Loening

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Protein science : a publication of the Protein Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Exploration of the interaction between dynein intermediate chain and dynactin p150Protein science : a publication of the Protein Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

A J Di NicolaDepartment of Chemistry, Lewis & Clark College, Portland, Oregon, USA.
Bryn L RomigDepartment of Chemistry, Lewis & Clark College, Portland, Oregon, USA.
Stella M DavisDepartment of Chemistry, Lewis & Clark College, Portland, Oregon, USA.
Paul H ClearyDepartment of Chemistry, Lewis & Clark College, Portland, Oregon, USA.
Claire H YungDepartment of Chemistry, Lewis & Clark College, Portland, Oregon, USA.
Daniel R MarsanDepartment of Chemistry, Lewis & Clark College, Portland, Oregon, USA.
Anna C MerktDepartment of Chemistry, Lewis & Clark College, Portland, Oregon, USA.
Nikolaus M LoeningDepartment of Chemistry, Lewis & Clark College, Portland, Oregon, USA.ORCID 0000-0002-5074-6906

Funding

M. J. Murdock Charitable Trust 201811283National Science Foundation 1917696National Science Foundation 2003557
6 · The paper itself

Abstract

Cytoplasmic dynein is a motor protein that plays a role in a number of cellular processes including retrograde transport. In many cases, dynein needs to interact with another protein, dynactin, to be fully active. An important step in the assembly of the dynein/dynactin complex is the interaction between the N-terminal portion of the intermediate chain (IC) subunit of dynein and the coiled-coil 1B (CC1B) region of the p150

Indexed as

Dynactin ComplexDyneinsAnimalsBinding SitesHumansModels, MolecularProtein BindingDynactin ComplexDyneinscoiled‐coilsdynactin p150Glueddynein intermediate chainintrinsically disordered proteinsisothermal titration calorimetrynuclear magnetic resonance spectroscopyphosphorylation

Identifiers

PMID40713938
PMCPMC12679947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.