Trial reportTrials2025
Effects of isoinertial training on muscle power, endurance, isometric strength, and balance: randomized clinical trial in patients with post-ACL reconstruction.
Trial report in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effectiveness of strength-oriented rehabilitation interventions as a non-pharmacologic rehabilitation strategy for knee function after anterior cruciate ligament reconstruction: a three-level meta-analysis.Frontiers in medicine · 2026Pooled it
- Comparative effectiveness of resistance training modalities after anterior cruciate ligament reconstruction: a network meta-analysis of randomized controlled trials.Frontiers in physiology · 2026Pooled it
- Effects of early inertial exercises on morphological and functional recovery after ACL reconstruction.Scientific reports · 2026Trial
- Residual Neuromuscular Deficits Following Anterior Cruciate Ligament Reconstruction Revealed by Phase-Specific Force, Electromyographic Complexity and Inter-Limb Asymmetries in Flywheel Squat.Sensors (Basel, Switzerland) · 2026Article
- Eccentric-Oriented Strength Training in Anterior Cruciate Ligament Rehabilitation: A Scoping Review.Medicina (Kaunas, Lithuania) · 2026Article
- The Impact of Isoinertial Training on Thigh Muscle Volume: Ultrasound and Dynamometric Evaluation.Bioengineering (Basel, Switzerland) · 2025Article
- The impact of exercise therapy on rehabilitation outcomes after anterior cruciate ligament reconstruction: a network meta-analysis.BMC musculoskeletal disorders · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundACL reconstruction surgery leads to temporary limitations in knee movement due to weakness in the quadriceps, swelling, and stiffness. Effective therapy is necessary to regain strength and functionality. While flywheel resistance training enhances strength and eccentric loading, there is limited knowledge about its effectiveness in conjunction with conventional rehabilitation methods. This study evaluates the impact of both conventional rehabilitation and isoinertial therapy on muscle power, endurance, isometric strength, and balance in patients following ACL repair.
methodsA total of 96 out of 136 patients aged 18 to 45 who had been randomly assigned to groups were included 3 weeks post-procedure. Over 6 weeks, 47 patients in group A (n = 47) participated in both isoinertial training and conventional therapy protocals while in group B (n = 49) followed a conventional rehabilitation protocol for just 30 min daily. To assess the patients' muscle power, endurance, isometric strength, and balance, a flywheel ergometer (D11 Plus; Desmotec, Biella, Italy) was utilized both before and after the 6-week treatment period.
resultsGroup A had statistically significant increases in eccentric muscular power (p = 0.0001), whereas there was no noticeable difference between the two groups in isometric strength, balance, or concentric power (p = 0.731, p = 0.786, and p = 0.815, respectively).
conclusionThe finding indicates that isometric strength, balance, and both concentric and eccentric muscular power were successfully improved by both 6-week interventions: traditional rehabilitation alone and in conjunction with isoinertial training. But when compared to traditional therapy alone, the isoinertial training group showed better gains in muscular endurance. There were no discernible variations in the groups' isometric strength or balance results. The study also emphasizes how isoinertial training can effectively increase eccentric power.
trial registrationThe ethics approval number is LPU/IEC/2018/01/09. Registered in the Clinical Trials Registry of India under CTRI/2019/06/019858 dated 23/09/2021.
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