Evidence map›Paper›PMID 40713587›Full record

Trial reportBMC oral health2025

Comparative efficacy of laser and electroacupuncture on anxiety management and salivary alpha-amylase levels in pediatric dental patients with excessive gag reflexes: a randomized clinical trial.

Marwa Baraka, Sarah I Zeitoun, Sara Salah, Sawsan Hafez

Registry-linked trialAbstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06422286 (Efficacy of Low-level Laser Acupuncture and Microcurrent Electrical Stimulation on Gag Reflex on Children During Taking Dental Impression), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06422286 naunknown statusnot on this map

Efficacy of Low-level Laser Acupuncture and Microcurrent Electrical Stimulation on Gag Reflex on Children During Taking Dental Impression

TypeinterventionalSponsorAlexandria UniversityRan2024 to 2024Enrolled63ConditionsGaggingArmslow-level laser, microcurrent stimulation, placebo
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marwa BarakaFaculty of Dentistry, Pediatric Dentistry and Dental Public Health Department, Alexandria University, Champollion St., El Azareta, Alexandria, Egypt. marwa.baraka@alexu.edu.eg.ORCID http://orcid.org/0000-0001-7259-5515
Sarah I ZeitounFaculty of Dentistry, Pediatric Dentistry and Dental Public Health Department, Alexandria University, Champollion St., El Azareta, Alexandria, Egypt.
Sara SalahFaculty of Dentistry, Pediatric Dentistry and Dental Public Health Department, Alexandria University, Champollion St., El Azareta, Alexandria, Egypt.
Sawsan HafezFaculty of Dentistry, Pediatric Dentistry and Dental Public Health Department, Alexandria University, Champollion St., El Azareta, Alexandria, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study examines the effects of laser acupuncture and electroacupuncture on anxiety in children with excessive gag reflexes during dental impressions.

methodsA three-armed randomized controlled trial involved 63 pediatric dental patients aged 6-9 with excessive gag reflexes. Participants were equally divided into three groups: group 1 (laser acupuncture), group 2 (electroacupuncture), and group 3 (negative control with a deactivated device). Salivary alpha-amylase (sAA) levels, Frankl scores, facial image scale (FIS), and heart rate were measured before and after interventions to assess dental anxiety. Group comparisons were conducted using one-way ANOVA or Kruskal-Wallis tests, followed by Bonferroni-corrected pairwise comparisons for significant results, with significance defined as p < 0.05.

resultsThe study found no significant differences in sAA levels before the intervention, but electroacupuncture significantly reduced levels post-intervention (p = 0.009) compared to the laser and control groups. Frankl scores also improved significantly with electroacupuncture (p = 0.002), indicating better cooperation during dental procedures. Both electroacupuncture and laser groups reduced heart rates significantly compared to control (p < 0.001), with correlations indicating that higher sAA levels were associated with increased discomfort in the laser group, and that stress levels were linked to heart rate in the control group.

conclusionsBoth laser acupuncture and electroacupuncture effectively lowered anxiety level in children with gag reflex. While both methods improved objective and subjective scores, electroacupuncture demonstrated superior efficacy in managing anxiety. CLINICAL RELEVANCE: These findings support acupuncture techniques as valuable tools in pediatric dentistry for improving patient cooperation and managing anxiety during dental procedures.

trial registrationRegistered on clinicaltrial.gov; NCT06422286, 16/4/2024.

Indexed as

Dental AnxietyElectroacupunctureGaggingSalivaSalivary alpha-AmylasesChildFemaleHeart RateHumansMaleTreatment OutcomeSalivary alpha-AmylasesAcupunctureAlginate impressionDental anxietyGag reflexLaserPediatric dentistrySalivary amylase

Identifiers

PMID40713587
PMCPMC12297650

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.