Evidence map›Paper›PMID 40713502›Full record

ArticleBMC neuroscience2025

Effects of repetitive mechanical tactile stimulation interventions with stationary and moving patterns on paired-pulse depression.

Hiraku Watanabe, Sho Kojima, Naofumi Otsuru, Hideaki Onishi

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Hiraku WatanabeDivision of Physical Therapy and Rehabilitation Medicine, University of Fukui Hospital, 23-3, Matsuoka Shimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui, Japan. hiraku@u-fukui.ac.jp.
Sho KojimaInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, 1398 Shimami-cho, Kita-ku, Niigata, Niigata, 950-3198, Japan.
Naofumi OtsuruInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, 1398 Shimami-cho, Kita-ku, Niigata, Niigata, 950-3198, Japan.
Hideaki OnishiInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, 1398 Shimami-cho, Kita-ku, Niigata, Niigata, 950-3198, Japan.

Funding

Grant-in-Aid program from Niigata University of Health and Welfare R02B03Grant-in-Aid program from Niigata University of Health and Welfare R02F09Japan Society for the Promotion of Science 19H01090Japan Society for the Promotion of Science 23K21589
6 · The paper itself

Abstract

backgroundRepetitive somatosensory stimulation (RSS) reduces paired-pulse depression (PPD), reflecting GABAergic inhibition in the primary somatosensory cortex (S1). This effect may vary by tactile stimulation pattern. Therefore, this study aimed to clarify the effects of RSS intervention with stationary and moving pattern tactile stimulation on PPD.

resultsIn a crossover study of 15 healthy males, RSS with a stationary pattern showed a non-significant trend toward increased PPD (corrected p = 0.088), while the moving pattern showed no effect. A strong negative correlation was found between baseline PPD and its change rate (r = - 0.837, p < 0.001), indicating that greater baseline S1 inhibition predicted a larger reduction after RSS.

conclusionRSS effects on GABAergic inhibition in S1 depend on the tactile stimulation pattern, emphasizing the importance of tactile stimulus design in modulating somatosensory cortex activity.

Indexed as

Evoked Potentials, SomatosensoryNeural InhibitionSomatosensory CortexTouchTouch PerceptionAdultCross-Over StudiesHumansMalePhysical StimulationYoung AdultElectroencephalographyPaired-pulse depressionRepetitive somatosensory stimulationSomatosensory-evoked potentials

Identifiers

PMID40713502
PMCPMC12297507

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.