Evidence map›Paper›PMID 40713174›Full record

ArticleThe Journal of rheumatology2025

Cumulative Incidence of Cancer Screening for Breast, Cervical, Prostate, and Colorectal Cancer in Patients With Rheumatoid Arthritis.

Rebecca T Brooks, Cassondra A Hulshizer, Andrew C Hanson, John M Davis, Vanessa L Kronzer, Elena Myasoedova, Cynthia S Crowson

Abstract read
In one paragraph

Article in The Journal of rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rebecca T BrooksR.T. Brooks, MD, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota.ORCID 0009-0000-0057-4512
Cassondra A HulshizerC.A. Hulshizer, BA, A.C. Hanson, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota.
Andrew C HansonC.A. Hulshizer, BA, A.C. Hanson, MS, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota.
John M DavisJ.M. Davis III, MD, MS, V.L. Kronzer, MD, MSCI, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota.
Vanessa L KronzerJ.M. Davis III, MD, MS, V.L. Kronzer, MD, MSCI, Division of Rheumatology, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0002-7489-3134
Elena MyasoedovaE. Myasoedova, MD, PhD, C.S. Crowson, PhD, Department of Quantitative Health Sciences, Mayo Clinic, and Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0003-2006-1436
Cynthia S CrowsonE. Myasoedova, MD, PhD, C.S. Crowson, PhD, Department of Quantitative Health Sciences, Mayo Clinic, and Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA. crowson@mayo.edu.ORCID 0000-0001-5847-7475

Funding

HEART DISEASE IN RHEUMATOID ARTHRITISR01AR046849 · NIAMS · MAYO CLINIC ROCHESTER · PI CROWSON, CYNTHIA S · 2000 to 2022
$11.3M
Role of Systemic Inflammation in Cognitive Decline: Rheumatoid Arthritis as a PrototypeR01AG068192 · NIA · MAYO CLINIC ROCHESTER · PI Elena Myasoedova · 2020 to 2026
$4.4M
Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology ProjectR33AG058738 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, OLSON, JANET E · 2020 to 2022
$2.4M
Temporal associations between systemic inflammation, cardiovascular risk profile and development of Alzheimer’s disease and related dementias in patients with rheumatoid arthritisK24AG078179 · NIA · MAYO CLINIC ROCHESTER · PI Elena Myasoedova · 2022 to 2026
$951k
Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology ProjectR21AG058738 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, OLSON, JANET E · 2018 to 2019
$437k
NIAMS NIH HHS R01 AR046849NIA NIH HHS K24 AG078179NIA NIH HHS R01 AG068192NIA NIH HHS R21 AG058738NIA NIH HHS R33 AG058738
6 · The paper itself

Abstract

objectiveTo determine the incidence of breast, cervical, prostate, and colorectal cancer screening in patients with rheumatoid arthritis (RA) vs matched non-RA comparators.

methodsWe performed a retrospective, matched cohort study of patients with and without RA living in an 8-county region of southern Minnesota on January 1, 2015. Through review of medical records, patients who fulfilled either the 1987 American College of Rheumatology (ACR) or 2010 ACR/European Alliance of Associations for Rheumatology classification criteria for RA were identified. Patients with RA were matched 1:1 to non-RA comparators on age, sex, and county of residence. Cancer screening was determined from review of the US Preventative Task Force recommendations. Cumulative incidence of cancer screening was estimated accounting for the competing risk of death, and Cox proportional hazard models adjusted for age, smoking, and race assessed for the risk of delay.

resultsThe study included 1614 patients with RA and 1597 comparators without RA (mean age 63 years, 71% female). At 5-years of follow-up, 51.6% (95% CI 47.9-55.6) of the RA cohort had cervical cancer screening compared to 58.2% (95% CI 54.5-62.2) in the non-RA cohort. After adjusting for age, smoking, and race, RA was associated with decreased cervical cancer screening (adjusted hazard ratio [aHR] 0.83, 95% CI 0.72-0.96). RA was not significantly associated with a decrease in breast (aHR 0.98, 95% CI 0.87-1.10), prostate (aHR 0.99, 95% CI 0.74-1.34), or colorectal (aHR 1.04, 95% CI 0.93-1.16) cancer screening.

conclusionWomen with RA were more likely to experience delayed cervical cancer screening. Increased diligence by healthcare providers to ensure cervical cancer screening in patients with RA is important to reduce the morbidity and mortality seen in these patients.

Indexed as

Arthritis, RheumatoidBreast NeoplasmsColorectal NeoplasmsEarly Detection of CancerProstatic NeoplasmsUterine Cervical NeoplasmsAgedFemaleHumansIncidenceMaleMiddle AgedMinnesotaProportional Hazards ModelsRetrospective Studiesmortalitypreventive medicinerheumatoid arthritis

Identifiers

PMID40713174
PMCPMC12313206

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.