ArticleJACC. Case reports2025
Cardio-Embolic Stroke in a 14-Year-Old Boy Due to SCN5A-Associated Atrial Standstill.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAtrial standstill is a rare pathologic phenomenon characterized by absence of electrical and mechanical activity of one or both atria. SCN5A gene mutations are associated with a myriad of clinical cardiac phenotypes including sinus node dysfunction and atrial standstill. CASE SUMMARY: We present a case of a 14-year-old boy who suffered acute embolic stroke in the setting of SNC5A-associated atrial standstill. The patient required thrombolysis and interventional thrombectomy, after which he recovered completely. DISCUSSION: To our knowledge, this is the first report of acute embolic stroke as the initial presentation of SCN5A-associated partial atrial standstill in the pediatric population. SCN5A-associated atrial standstill carries a significant risk of stroke and mortality in pediatric patients who are not identified and managed appropriately. TAKE-HOME MESSAGES: Atrial standstill can present with serious cardioembolic complications in pediatric patients. Prevention using oral anticoagulation should be considered in patients with partial atrial standstill, especially when associated with SCN5A variants and in the absence of atrial pacing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.