ArticleJACC. Case reports2025
Intracardiac Leiomyoma Leading to Liver Failure and Heart Failure Managed by VA-ECMO and Surgical Resection.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundIntracardiac leiomyomatosis (ICL), a rare condition characterized by intracardiac tumors, can be associated with uterine leiomyomas. Early diagnosis is crucial due to the risk of severe cardiac complications. CASE SUMMARY: A 52-year-old woman presented with severe liver failure and heart failure caused by a large right ventricular leiomyoma. The patient was managed with venoarterial extracorporeal membrane oxygenation (ECMO) support and subsequent surgical resection of the tumor. Histological examination confirmed a benign smooth muscle tumor. DISCUSSION: This case highlights the challenges in diagnosing and managing ICL, particularly when presenting with multiorgan failure. ECMO served as a vital bridge to surgery. ICL should be considered in patients with right-sided intracardiac masses, especially with a history of hysterectomy. TAKE-HOME MESSAGES: ICL is a rare, but life-threatening, condition of intracardiac tumors. Early diagnosis and aggressive management, including ECMO as a bridging therapy, are crucial for improved outcomes.
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