Evidence map›Paper›PMID 40713084›Full record

SynthesisBMJ global health2025

Cross-national research on adolescent mental health: a systematic review comparing research in low, middle and high-income countries.

Xiao Zhang, Yuko Mori, Anne Abio, Zahra Kafami Khorasani, Sonja Gilbert, Meytal Grimland, Nikita Bezborodovs, Wan Mohd Azam Wan Mohd Yunus, Sanju Silwal, Minja Westerlund and 5 more

Abstract readSystematic Review
In one paragraph

Synthesis in BMJ global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xiao ZhangDepartment of Child Psychiatry, Research Centre for Child Psychiatry, University of Turku, Turku, Finland.
Yuko MoriDepartment of Child Psychiatry, Research Centre for Child Psychiatry, University of Turku, Turku, Finland yumori@utu.fi.ORCID http://orcid.org/0000-0003-3589-6866
Anne AbioDepartment of Child Psychiatry, Research Centre for Child Psychiatry, University of Turku, Turku, Finland.ORCID http://orcid.org/0000-0002-4568-3509
Zahra Kafami KhorasaniDepartment of Child Psychiatry, Research Centre for Child Psychiatry, University of Turku, Turku, Finland.
Sonja GilbertDepartment of Child Psychiatry, Research Centre for Child Psychiatry, University of Turku, Turku, Finland.
Meytal GrimlandINVEST Research Flagship Center, University of Turku, Turku, Finland.
Nikita BezborodovsDepartment of Psychiatry and Narcology, Riga Stradins University, Riga, Latvia.
Wan Mohd Azam Wan Mohd YunusFaculty of Social Sciences and Humanities, Universiti Teknologi Malaysia, Johor, Malaysia.
Sanju SilwalDepartment of Child Psychiatry, Research Centre for Child Psychiatry, University of Turku, Turku, Finland.
Minja WesterlundDepartment of Child Psychiatry, Research Centre for Child Psychiatry, University of Turku, Turku, Finland.
Samir Kumar PraharajDepartment of Psychiatry, Kasturba Medical College, Manipal, India.
David M NdeteiAfrica Institute of Mental and Brain Health, Nairobi, Kenya.
Hitoshi KanekoPsychological Support and Research Center for Human Development, Nagoya University, Nagoya, Japan.
Emmi HeinonenDepartment of Child Psychiatry, Research Centre for Child Psychiatry, University of Turku, Turku, Finland.
Andre SouranderINVEST Research Flagship Center, University of Turku, Turku, Finland.ORCID http://orcid.org/0000-0003-0361-7244

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough 90% of the global adolescent population resides in low and middle-income countries (LMICs), cross-national mental health research has primarily focused on high-income countries. This systematic review aims to examine cross-national studies, including LMICs, focusing on adolescent mental health and psychosocial problems.

methodsPeer-reviewed articles comparing adolescent mental health or psychosocial issues across countries were included if published in English and based on observational study designs. Six databases were searched from inception to January 2024. Risk of bias was assessed using the JBI tool and additional cross-national quality criteria. A narrative synthesis was conducted following the Synthesis Without Meta-analysis guidelines.

resultsThe search identified 172 studies including data from over 12 million adolescents across 166 countries. The most used international survey was the Health Behaviour in School-aged Children study, and most studies employed cross-sectional designs with school-based, self-reported questionnaires. Adolescent mental health research involved 166 countries, while 52 countries were not represented in any of the studies. The inclusion of LMICs in cross-national research increased over time. Internalising problems and bullying were well-researched topics, but studies on externalising behaviours were limited. The number of publications increased over time, particularly after 2020. Variations by income level were observed, with traditional bullying more prevalent in LMICs. DISCUSSION: This review provides important insights into global patterns and gaps in adolescent mental health research. It highlights the need to address methodological heterogeneity, including the use of validated and culturally adapted measures, comprehensive reporting of sampling procedures, sample sizes, response rates and greater attention to generalisability. In addition, the targeted inclusion of under-represented regions is essential to addressing global disparities and informing effective interventions. PROSPERO REGISTRATION NUMBER: CRD42024505077.

Indexed as

Adolescent HealthDeveloped CountriesDeveloping CountriesMental HealthAdolescentHumansEpidemiologyGlobal HealthMental Health & PsychiatryPublic HealthSystematic review

Identifiers

PMID40713084
PMCPMC12306219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.