ReviewCell genomics2025
How exposomic tools complement and enrich genomic research.
Review in Cell genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Environmental exposures and multiple myeloma risk: A contemporary review of epidemiologic associations and mechanistic plausibility.Blood reviews · 2026Review
- Decoding causal m6A: a bioinformatics roadmap for psychiatric disorders.Briefings in bioinformatics · 2026Review
- Oxidative Stress, Environmental Pollutants, Aging, and Epigenetic Regulation: Mechanistic Insights and Biomarker Advances.Antioxidants (Basel, Switzerland) · 2026Review
- A biobank-scale method for learning modulators of gene-environment interaction underlying human complex traits from multiple environmental exposures.bioRxiv : the preprint server for biology · 2026Article
- Reforming schools into health promoting schools: perspective based on expert consensus from a European multistakeholder consultation.European journal of pediatrics · 2026Article
- Genetic and Environmental Factors Shaping Hearing Loss: Xenobiotics, Mechanisms and Translational Perspectives.Journal of xenobiotics · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Because genetics and the environment interact to drive gene expression, we propose that exposomics must now be incorporated into the multi-omics paradigm to complete the overall biological pathway. Exposomics' groundbreaking tools and life-course framework holistically characterize non-genetic (environment) components of chronic diseases and integrate with multi-omics. This work brings forward the importance of the human exposome as a major driver of gene/protein expression across the life course. Exposome features are noteworthy for multi-omics as they (1) show where and when biodynamic trajectories of gene x environment interactions meet; (2) move beyond single-environmental-factor-centric views; (3) integrate exposomic measurements during and outside of critical windows of susceptibility; (4) provide agnostic discovery and hypothesis-generating studies; and (5) are biodynamic over time. Upon applying these unique features of the human exposome, future human studies are anticipated to revolutionize the integration of genetics and environmental health sciences.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.