Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
32 authors.
Jingxin LiuDepartment of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.ORCID 0009-0003-7861-0626
Cai ZhaoDepartment of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.ORCID 0009-0004-9884-8698
Jiahao ChenDepartment of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.ORCID 0009-0001-3413-5005
Pengguihang ZengDepartment of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.ORCID 0000-0002-1686-436X
Qingjian LiDepartment of Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.ORCID 0000-0003-3453-6316
Ranran DaiDepartment of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.ORCID 0000-0003-4044-2615
Xingqiang LaiKey Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.ORCID 0000-0002-6390-9938
Wenqian SongState Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, Shanghai, 200031, China.ORCID 0009-0008-1280-0204
Jianing ChenBreast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.ORCID 0000-0002-2748-5197
Xixi ZhuSchool of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, 511436, China.ORCID 0009-0001-0384-9339
Xinyi LiuDepartment of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.ORCID 0000-0003-0241-5499
Jun SunDepartment of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.ORCID 0000-0003-1190-3937
Jia WangDepartment of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.
Peihang FangDepartment of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.
Tengfei WangDepartment of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.
Wenjie ChenVaccine Research Institute, The Third Affiliated Hospital of Sun Yat-sen University, Sun Yat-sen University, Guangzhou, 510630, China.ORCID 0009-0000-0635-7746
Diana GuallarCenter for Research in Molecular Medicine and Chronic Diseases (CiMUS), Universidade de Santiago de Compostela (USC)-Health Research Institute (IDIS), Santiago de Compostela, 15782, Spain.ORCID 0000-0001-5834-7507
Nan CaoKey Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.ORCID 0000-0002-1660-4728
Jianli ZhaoDepartment of Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.ORCID 0000-0003-1980-3236
Shicheng SuBreast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.ORCID 0000-0003-2280-3587
Andy Peng XiangKey Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.ORCID 0000-0003-3409-5012
Yi Arial ZengState Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, Shanghai, 200031, China.ORCID 0000-0003-1898-8099
Jie LiDepartment of Breast and Thyroid Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510275, China.ORCID 0000-0003-1232-3248
Junchao CaiDepartment of Immunology, Sun Yat-sen University Zhongshan School of Medicine, Guangzhou, 510080, China.ORCID 0000-0001-8412-6177
Dung-Fang LeeDepartment of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.ORCID 0000-0003-2387-597X
Jinxin BeiSun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060 China.ORCID 0000-0003-1333-407X
Yongliang HuoSchool of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, 511436, China.ORCID 0000-0003-3880-8622
Hai HuBreast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.ORCID 0000-0001-6338-7431
Dong-Feng HuangDepartment of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.ORCID 0000-0002-7958-4082
Jin BaiCancer Institute, Xuzhou Medical University, 221002, Jiangsu, China.ORCID 0000-0001-5266-6582
Junjun DingDepartment of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.ORCID 0000-0002-9936-882X
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
Breast cancer is the most common malignancy in females and remains the leading cause of cancer-related deaths for women worldwide. The cellular and molecular basis of breast tumorigenesis is not completely understood partly due to the lack of human research models which simulate the development of breast cancer. Here, we developed a method for generating functional mammary-like cells (MCs) from human-induced pluripotent stem cells (iPSCs). The iPSC-MCs closely resemble human primary MCs at cellular, transcriptional, and functional levels. Using this method, a breast cancer model was generated using patient-derived iPSCs harboring germline
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Human iPSC-based breast cancer model identifies S100P-dependent cancer stemness induced by · full record | OpenQuestion