Evidence map›Paper›PMID 40711889›Full record

ArticlePlant biotechnology journal2025

Heterologous expression of Arabidopsis FLS2 in Nicotiana benthamiana confers responsiveness to Ralstonia flg22 and activation of anti-bacterial immunity.

Meng Li, Yujiao Chen, Yali Wei, Alberto P Macho

Abstract read
In one paragraph

Article in Plant biotechnology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Tomato activates ethylene signaling to maintainFrontiers in plant science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Meng Li *Shanghai Center for Plant Stress Biology, Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, China.
Yujiao Chen *Shanghai Center for Plant Stress Biology, Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, China.
Yali WeiShanghai Center for Plant Stress Biology, Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, China.
Alberto P MachoShanghai Center for Plant Stress Biology, Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, China.

Funding

Chinese Academy of SciencesNational Natural Science Foundation of China 32350710194
6 · The paper itself

Abstract

The association between Arabidopsis FLS2 and BAK1/SERK3 triggered by bacterial flagellin is the best-studied example of plant PRR receptor/co-receptor complex. Although most plants are able to perceive the flagellin epitope flg22 from most bacterial species, certain pathogens, such as Agrobacterium tumefaciens or Ralstonia solanacearum, have evolved polymorphisms in their flg22 sequence, avoiding perception by most plants tested so far. Specific plant species, such as Vitis riparia or Glycine max, respectively, have subsequently evolved FLS2 versions with the ability to recognize these polymorphic flg22 peptides. The model plants Arabidopsis or N. benthamiana are not able to perceive the flg22 peptide from R. solanacearum (flg22

Indexed as

ArabidopsisArabidopsis ProteinsFlagellinNicotianaPlant DiseasesPlant ImmunityProtein KinasesRalstonia solanacearumGene Expression Regulation, PlantPlants, Genetically ModifiedArabidopsis ProteinsFlagellinFLS2 protein, ArabidopsisProtein KinasesArabidopsisbenthamianaflagellinflg22FLS2Ralstonia

Identifiers

PMID40711889
PMCPMC12576447

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.