SynthesisThe British journal of radiology2025
Pulmonary hypertension and the role of MRI flow assessment: a systematic review.
Synthesis in The British journal of radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic Performance of Magnetic Resonance Imaging in Chronic Thromboembolic Pulmonary Hypertension: A Systematic Review.Journal of medical imaging and radiation oncology · 2026Pooled it
- Automated CMR Quantification of Pulmonary Artery Size-Based and Slow-Flow Metrics in Pulmonary Hypertension.Diagnostics (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
objectivesCardiac magnetic resonance imaging (CMR) plays an increasingly important role in non-invasive assessment of pulmonary hypertension (PH). This systematic review aimed to assess the utility, accuracy, and clinical applications of CMR flow techniques in evaluating pulmonary arterial blood flow in patients with suspected or confirmed PH.
methodsMEDLINE and EMBASE databases were searched on December 10, 2024, utilizing the following key terms: "cardiac MRI," "flow," and "pulmonary hypertension." Eligible studies were screened, and data extraction included study design, cohort characteristics, CMR flow techniques and outcomes. Risk of bias was assessed using the Newcastle-Ottawa scale.
resultsThirty-eight studies (mean sample size: 30 [20-57]) published between 2012 and 2024 were included. These utilized 2D flow (19 studies), 4D flow (15 studies), black blood imaging (1 study) and combined flow techniques (3 studies). Vortex duration derived by 4D flow demonstrated the strongest correlation (r = 0.96) with mean pulmonary artery pressure and the highest diagnostic accuracy in identifying PH patients (area under the curve, 0.99). Risk of bias rated 14 studies as good/very good and 13 as unsatisfactory, with none justifying their sample size selection.
conclusionCMR flow parameters correlate strongly with right heart catheterization measurements and demonstrate high diagnostic accuracy in identifying patients with PH, with 4D flow potentially adding greater value. This systematic review reinforces the potential benefit of CMR flow techniques in the investigation, prognostication, and monitoring of PH patients. ADVANCES IN KNOWLEDGE: This systematic review is the first to evaluate the role of CMR flow techniques in PH and should inform guidelines on flow assessment in PH.
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