Evidence map›Paper›PMID 40711855›Full record

ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2025

Optimism and cognitive functioning trajectories in a cohort of aging men.

Victoria R Marino, Laura D Kubzansky, Francine Grodstein, Samsuk Kim, Avron Spiro, Lewina O Lee

Abstract read
In one paragraph

Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Victoria R MarinoBehavioral Science Division, National Center for Posttraumatic Stress Disorder, VA Boston Healthcare System, Boston, Massachusetts, United States.ORCID 0000-0001-8403-6083
Laura D KubzanskyDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States.ORCID 0000-0002-4039-2235
Francine GrodsteinRush Alzheimer's Disease Center, Chicago, Illinois, United States.
Samsuk KimDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California, United States.ORCID 0000-0001-8893-2248
Avron SpiroCooperative Studies Program Coordinating Center, VA Boston Healthcare System, Boston, Massachusetts, United States.ORCID 0000-0003-4080-8621
Lewina O LeeBehavioral Science Division, National Center for Posttraumatic Stress Disorder, VA Boston Healthcare System, Boston, Massachusetts, United States.ORCID 0000-0002-1652-8198

Funding

PERSONALITY AND WELL BEING TRAJECTORIES IN ADULTHOODR01AG018436 · NIA · PURDUE UNIVERSITY WEST LAFAYETTE · PI MROCZEK, DANIEL K. · 2000 to 2020
$6.7M
Boston Early Adversity and Mortality Study (BEAMS): Linking Administrative Data to Long-Term Longitudinal StudiesRF1AG064006 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEE, LEWINA ONYI, MROCZEK, DANIEL K. · 2019 to 2023
$3.8M
NIA NIH HHS R01 AG018436NIA NIH HHS RF1 AG064006NIH HHS K08-048221NIH HHS R01-AA008941NIH HHS R01-AG002287NIH HHS R01-AG018436NIH HHS RF1-AG064006
6 · The paper itself

Abstract

objectivesRobust evidence supports optimism as an asset for good physical and emotional health in aging populations, but its role in cognitive aging remains understudied. This study evaluated whether higher optimism levels would be prospectively associated with higher initial levels and slower decline in cognitive functioning over 26 years in a community-dwelling cohort of aging men.

methodsParticipants included 847 men from the Veterans Affairs Normative Aging Study who completed the Revised Optimism-Pessimism scale of the Minnesota Multiphasic Personality Inventory-2 in 1986 and ≥1 cognitive assessment repeated triennially in 1993-2019. At each assessment, scores from seven cognitive tests were combined into a global composite and three domain-specific composites: verbal memory, executive functioning, and visuospatial ability. Mixed-effects regression models evaluated the associations between optimism and cognitive trajectories.

resultsHigher optimism levels were associated with higher initial levels but not less decline in global cognitive functioning over time (B = 0.04, 95% CI: 0.001-00.07), , adjusted for demographics, practice effects, and lag between optimism assessment and the first cognitive assessment. In domain-specific analyses, optimism was associated with higher initial levels but not magnitude of decline in verbal memory (B = 0.06, 95% CI: 0.01-0.12), and unrelated to executive functioning or visuospatial ability trajectories. DISCUSSION: This study adds specificity to a nascent literature linking optimism to cognitive aging, indicating an association with initial levels, but not decline-particularly in verbal memory-in older men. Examining these relationships earlier in life may further clarify the etiologic role of optimism in cognitive health across the developmental span.

Indexed as

AgingCognitionCognitive AgingCognitive DysfunctionExecutive FunctionOptimismAgedAged, 80 and overCohort StudiesHumansLongitudinal StudiesMaleMiddle AgedNeuropsychological TestsCognitionMemoryPersonalityWell-being

Identifiers

PMID40711855
PMCPMC12471349

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.