Evidence map›Paper›PMID 40711626›Full record

ArticleHealth & justice2025

Overdose education and naloxone distribution in jails: Examining the impact of the Communities That HEAL intervention in 4 states.

Timothy Hunt, Carrie B Oser, Peter D Friedmann, Nicole Mack, Peter Balvanz, Bridget Freisthler, Redonna K Chandler, Karli Hochstatter, Daniel R Harris, LaShawn Glasgow and 33 more

Abstract read
In one paragraph

Article in Health & justice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

43 authors.

Timothy HuntColumbia University School of Social Work, New York, USA. th2258@columbia.edu.
Carrie B OserDepartment of Behavioral Science, Center on Drug & Alcohol Research, Center for Health, Engagement and Transformation, University of Kentucky, Lexington, USA.
Peter D FriedmannBaystate Health and University of Massachusetts Chan Medical School- Baystate, Springfield, USA.
Nicole MackRTI International, Durham, USA.
Peter BalvanzGeneral Internal Medicine, Boston Medical Center, Boston, USA.
Bridget FreisthlerOhio State University, Columbus, USA.
Redonna K ChandlerNational Institutes of Health, Bethesda, USA.
Karli HochstatterFriends Research Institute, Baltimore, USA.
Daniel R HarrisCollege of Pharmacy, University of Kentucky, Lexington, USA.
LaShawn GlasgowRTI International, Durham, USA.
Lauren D'CostaRTI International, Durham, USA.
Mary R RussoColumbia University School of Social Work, New York, USA.
Barry EgglestonRTI International, Durham, USA.
Arnie AldridgeRTI International, Durham, USA.
Paul BellairOhio State University, Columbus, USA.
Allyson G CoganGeneral Internal Medicine, Boston Medical Center, Boston, USA.
James L DavidColumbia University School of Social Work, New York, USA.
Nabila El-BasselColumbia University School of Social Work, New York, USA.
Dawn Goddard-EckrichColumbia University School of Social Work, New York, USA.
Steve GomoriRTI International, Durham, USA.
Holly HaganNew York University, New York, USA.
Steve HansonAll Rise Treatment Court Institute, Alexandria, Virginia, USA.
JaNae HollowayRTI International, Durham, USA.
Elizabeth N KinnardGeneral Internal Medicine, Boston Medical Center, Boston, USA.
Charlie KnottRTI International, Durham, USA.
Michael W KonstanCase Western Reserve University, Cleveland, USA.
Sharon L WalshDepartment of Behavioral Science, Center on Drug & Alcohol Research, Center for Health, Engagement and Transformation, University of Kentucky, Lexington, USA.
Patricia A LeBaronRTI International, Durham, USA.
Michael S LyonsOhio State University, Columbus, USA.
Margaret McGladreyDepartment of Behavioral Science, Center on Drug & Alcohol Research, Center for Health, Engagement and Transformation, University of Kentucky, Lexington, USA.
Joan PappCase Western Reserve University, Cleveland, USA.
Sean M MurphyWeill Cornell Medical College, New York, USA.
Sandra SpringerYale School of Medicine, New Haven, USA.
Emmanuel OgaRTI International, Durham, USA.
Michele StatonDepartment of Behavioral Science, Center on Drug & Alcohol Research, Center for Health, Engagement and Transformation, University of Kentucky, Lexington, USA.
Elizabeth SchadyHealth Research, Inc., New York, USA.
Fernando MonteroColumbia University School of Social Work, New York, USA.
Hilary L SurrattDepartment of Behavioral Science, Center on Drug & Alcohol Research, Center for Health, Engagement and Transformation, University of Kentucky, Lexington, USA.
Danelle Stevens-WatkinsDepartment of Behavioral Science, Center on Drug & Alcohol Research, Center for Health, Engagement and Transformation, University of Kentucky, Lexington, USA.
John WinhusenUniversity of Cincinnati College of Medicine, Cincinnati, USA.
Gary A ZarkinRTI International, Durham, USA.
Greer A HamiltonSchool of Social Work, University of Michigan, Ann Arbor, USA.
Joel G SprungerUniversity of Cincinnati College of Medicine, Cincinnati, USA.

Funding

MassHEAL - Reducing overdose deaths by 40% (2019-2023)UM1DA049412 · NIDA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H. · 2019 to 2023
$82.9M
Kentucky CAN HEAL (Communities and Networks Helping End Addiction Long-term)UM1DA049406 · NIDA · UNIVERSITY OF KENTUCKY · PI WALSH, SHARON L. · 2019 to 2022
$81.7M
CHASE: An Innovative County-Level Public Health Response to the Opioid Epidemic in New York StateUM1DA049415 · NIDA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI EL-BASSEL, NABILA, GILBERT, LOUISA · 2019 to 2023
$77.3M
Optimizing HEALing in Ohio Communities (OHiO)-Health Equity SupplementUM1DA049417 · NIDA · OHIO STATE UNIVERSITY · PI FREISTHLER, BRIDGET J, WINHUSEN, T JOHN · 2019 to 2023
$66.3M
HEALing Communities Study Health Equity ResearchUM1DA049394 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI GLASGOW, LASHAWN, KNOTT, CHARLES · 2019 to 2023
$40.6M
NIDA NIH HHS UM1 DA049394NIDA NIH HHS UM1DA049394NIDA NIH HHS UM1 DA049406NIDA NIH HHS UM1 DA049412NIDA NIH HHS UM1 DA049415NIDA NIH HHS UM1 DA049417NIDA NIH HHS UM1DA049417
6 · The paper itself

Abstract

backgroundOpioid-related overdose is the leading cause of mortality among individuals recently released from incarceration in the U.S. Naloxone is an FDA-approved opioid antagonist medication designed to rapidly reverse opioid overdose. Despite evidence of its acceptability and effectiveness at reducing the risk of opioid overdose death after release from incarceration, only an estimated 25% of US jails provide naloxone upon release. This study examines the effectiveness of the HEALing Communities Study (HCS) Communities That HEAL (CTH) intervention on enhancing access to overdose education and naloxone distribution (OEND) in participating jails in Kentucky, New York, Massachusetts, and Ohio.

methodsCommunities were randomized to intervention (n = 34) or wait-list control (n = 33) arms stratified by state. Jail-based surveys (n = 59) were implemented at three time points during 2019 to 2022. Generalized linear mixed models (GLMM) with imputation captured intervention effects during the evaluation period (July 1, 2021-June 30, 2022). Interpretation of results was informed by the Practical, Robust Implementation and Sustainability Model framework.

resultsThe CTH intervention was significantly associated with the hypothesized outcome, resulting in a greater number of jails providing overdose education (H1, relative riskAdj = 1.51 [95% CI: 1.09, 2.08], p = 0.013) and the number of jails providing naloxone upon release (H2, relative riskAdj = 1.49 [95% CI: 1.05, 2.13)], p = 0.027). External factors related to OEND implementation, such as correctional health care models, available resources, and state COVID restrictions, varied across communities.

conclusionsThe CTH intervention engaging community coalitions to deploy evidence-based practices was effective in increasing OEND implementation in jails, helping address elevated overdose risks for individuals during and post-release from incarceration. Partnerships between state, community, and jail-based stakeholders are needed to assure expanded access to this lifesaving, evidence-based approach.

Indexed as

Carceral settingsJailNaloxone distributionOpioid epidemicOverdose education

Identifiers

PMID40711626
PMCPMC12296605

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.