Evidence map›Paper›PMID 40711537›Full record

ReviewDie Anaesthesiologie2025

[Bleeding disorders of unknown cause : Definition, diagnostics and management in the perioperative and periprocedural setting].

Jan Pilch, Sven Oliver Schneider, Julia Schulze-Berge, Marius Graf, Stefan Kleinschmidt

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In one paragraph

Review in Die Anaesthesiologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jan PilchInstitut für Transfusionsmedizin und Hämostaseologie, Universitätsklinikum Augsburg, Augsburg, Deutschland.
Sven Oliver SchneiderKlinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum des Saarlandes und Medizinische Fakultät, Universität des Saarlandes, 66421, Homburg (Saar), Deutschland.
Julia Schulze-BergeKlinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum des Saarlandes und Medizinische Fakultät, Universität des Saarlandes, 66421, Homburg (Saar), Deutschland.
Marius GrafKlinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum des Saarlandes und Medizinische Fakultät, Universität des Saarlandes, 66421, Homburg (Saar), Deutschland.
Stefan KleinschmidtKlinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum des Saarlandes und Medizinische Fakultät, Universität des Saarlandes, 66421, Homburg (Saar), Deutschland. Stefan.Kleinschmidt@uks.eu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perioperative and periprocedural bleeding complications substantially increase the morbidity and mortality. The main causes are intervention-related or trauma-related factors, patient-related factors, such as congenital or acquired hemostatic disorders as well as pre-existing medicinal anticoagulation as a result of the underlying disease. Despite the variety of currently available test procedures, the constellation of a clinically relevant bleeding situation without tangible pathological laboratory findings or causes often occurs. This constellation, called bleeding disorder of unknown cause (BDUC), requires a structured diagnostic and therapeutic approach to improve the outcome of the patient, to avoid a therapeutic polypragmasia and to limit the administration of hemostatics to that which is absolutely necessary. The close monitoring of these patients, whose quality of life is often restricted, is meaningful and necessary.

Indexed as

Blood Coagulation DisordersHemorrhagic DisordersPerioperative CareHemorrhageHumansBleeding assessment toolsBlood coagulationHemostaticsQuality of lifeRisk evaluation

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.