ArticleJapanese journal of ophthalmology2026
Tomographic and biomechanical refractive findings in ocular pediatric allergy.
Article in Japanese journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
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1 citing paper in PubMed.
- Analysis of corneal biomechanical characteristics and clinical correlations in children with dust mite-allergic conjunctivitis.Scientific reports · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate corneal tomographic and biomechanical refractive findings in ocular pediatric allergy to identify high-risk eyes for ectasia. STUDY
designA cross-sectional study
methodsFifty-seven patients (5-18 years), diagnosed with allergic conjunctival disease (ACD) between July 2022 and September 2023, underwent comprehensive ocular examinations and clinical assessments. The Ocular Allergy Severity Score (OCAS Score) was calculated to assess the severity of signs and symptoms. Tomographic-based and biomechanical parameters, including Corvis Biomechanical Index (CBI), Tomographic and Biomechanical Index (TBI), Belin/Ambrósio Deviation (BAD-D), and KISA% index, with a cut-off value of 0.5, 0.79, 2.6 and 100, respectively, were employed to identify corneal ectasia.
resultsAmong 57 patients, 54.4% were diagnosed with vernal keratoconjunctivitis, 26.3% with seasonal allergic conjunctivitis, and 19.3% with atopic keratoconjunctivitis. The itching was the most common initial ocular symptom, followed by irritation and redness. The high-risk eyes for ectasia (based on CBI, TBI, BAD-D, and KISA%) were identified in 23.7%, 19.3%, 13.2%, and 7.9%, respectively. The ectatic group (determined by TBI) exhibited significantly higher mean curvature power (Km) (46.48±3.64 vs 43.10±1.31, p<0.001) and lower central corneal thickness (525.09±42.21 vs 561.20±30.91, p<0.001). However, there was no significant difference in the severity score of signs and symptoms between ectatic and non-ectatic groups. Isoametropic amblyopia was identified in 8.8% of patients, and anisometropic amblyopia was present in 1.8%.
conclusionIn ocular pediatric allergy, the risk of developing corneal ectasia is unrelated to the severity of signs and symptoms. Therefore, routine tomographic and biomechanical evaluations are recommended.
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