Evidence map›Paper›PMID 40711331›Full record

ArticleVeterinary sciences2025

What Comes from Cytology Diagnosis: A Comprehensive Epidemiological Retrospective Analysis of 3068 Feline Cases.

Paula Brilhante-Simões, Ricardo Lopes, Leonor Delgado, Ana Machado, Augusto Silva, Ângela Martins, Ricardo Marcos, Felisbina Queiroga, Justina Prada

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Molecular Detection ofPathogens (Basel, Switzerland) · 2026
    Article
  2. Mapping Feline Oncology in Portugal: A National Characterization.Animals : an open access journal from MDPI · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Paula Brilhante-SimõesINNO Veterinary Laboratories, R. Cândido de Sousa 15, 4710-300 Braga, Portugal.ORCID 0000-0002-6124-2041
Ricardo LopesDepartment of Veterinary and Animal Sciences, University Institute of Health Sciences-CESPU (IUCS-CESPU), 4585-116 Gandra, Portugal.ORCID 0000-0002-9339-9932
Leonor DelgadoINNO Veterinary Laboratories, R. Cândido de Sousa 15, 4710-300 Braga, Portugal.ORCID 0000-0002-4405-0240
Ana MachadoINNO Veterinary Laboratories, R. Cândido de Sousa 15, 4710-300 Braga, Portugal.ORCID 0000-0003-3948-3014
Augusto SilvaINNO Veterinary Laboratories, R. Cândido de Sousa 15, 4710-300 Braga, Portugal.ORCID 0009-0005-3992-3771
Ângela MartinsAnimal and Veterinary Research Centre (CECAV), Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal.ORCID 0000-0003-1261-7027
Ricardo MarcosCytology and Hematology Diagnostic Services, Laboratory of Histology and Embryology, Department of Microscopy, ICBAS-School of Medicine and Biomedical Sciences, University of Porto (U.Porto), Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.ORCID 0000-0001-5502-5991
Felisbina QueirogaDepartment of Veterinary Sciences, University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal.ORCID 0000-0001-6130-8381
Justina PradaDepartment of Veterinary Sciences, University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal.ORCID 0000-0002-3902-5374

Funding

Fundação para a Ciência e Tecnologia UIDB/00772/2020
6 · The paper itself

Abstract

This study evaluated diagnostic trends and the overall utility of cytology in feline patients through the analysis of a large, multicentric dataset from Portugal. A retrospective review of 3068 cytological cases from 130 veterinary practices was conducted, with samples categorised by anatomical location and lesion type. Diagnostic outcomes were statistically assessed, revealing an overall success rate of 66.20%. The highest diagnostic yields occurred in fluid samples (83.48%), glandular tissues (76.67%), and mucous membranes (75.81%), followed by organ-based samples (67.79%), miscellaneous tissues (66.98%), cutaneous/subcutaneous nodules (62.16%), and lymph nodes (57.93%). Neoplastic lesions showed age-associated prevalence, being more common in older cats, with epithelial and melanocytic lesions more frequent in females and round cell/mesenchymal lesions predominating in males. Non-diagnostic samples (33.80%) primarily resulted from insufficient cellularity or suboptimal quality, though no significant correlation existed between diagnostic success and clinical setting. This study underscores that cytology remains a fundamental diagnostic tool in feline medicine, particularly when combined with proper sampling techniques and complementary diagnostic methods, and reinforces its value in clinical decision-making, thereby supporting its broader utilisation in routine veterinary practice.

Indexed as

anatomic locationcancercatclinical pathologycytologydiagnosisepidemiologyneoplasms

Identifiers

PMID40711331
PMCPMC12298540

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.