Evidence map›Paper›PMID 40711315›Full record

ArticleVeterinary sciences2025

Transcriptomic Insights into the Protective Effects of Apigenin and Sodium Butyrate on Jejunal Oxidative Stress in Ducks.

Ning Zhou, Hanxue Sun, Yong Tian, Heng Zhang, Xuemei Xian, Hui Yu, Lingyan Zhao, Yong Chen, Mingkun Sun, Yiqian Zhang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ning ZhouCollege of Pet Sciences, Jiangsu Agri-Animal Husbandry Vocational College, Taizhou 225300, China.
Hanxue SunZhejiang Provincial Key Laboratory of Livestock and Poultry Biotech Breeding, Key Laboratory of Livestock and Poultry Resources (Poultry) Evaluation and Utilization, Ministry of Agriculture and Rural Affairs, State Key Laboratory for Quality and Safety of Agro-Products, Institute of Animal Science & Veterinary, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Yong TianZhejiang Provincial Key Laboratory of Livestock and Poultry Biotech Breeding, Key Laboratory of Livestock and Poultry Resources (Poultry) Evaluation and Utilization, Ministry of Agriculture and Rural Affairs, State Key Laboratory for Quality and Safety of Agro-Products, Institute of Animal Science & Veterinary, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Heng ZhangCollege of Pet Sciences, Jiangsu Agri-Animal Husbandry Vocational College, Taizhou 225300, China.
Xuemei XianCollege of Pet Sciences, Jiangsu Agri-Animal Husbandry Vocational College, Taizhou 225300, China.
Hui YuZhejiang Xinchang Agricultural Development Co., Ltd., Lishui 321400, China.
Lingyan ZhaoZhejiang Provincial Center for Animal Disease Prevention and Control, Zhejiang Provincial Institute of Veterinary Drug and Feedstuff, Hangzhou 310021, China.ORCID 0009-0001-0710-3833
Yong ChenZhejiang Provincial Center for Animal Disease Prevention and Control, Zhejiang Provincial Institute of Veterinary Drug and Feedstuff, Hangzhou 310021, China.
Mingkun SunCollege of Pet Sciences, Jiangsu Agri-Animal Husbandry Vocational College, Taizhou 225300, China.
Yiqian ZhangCollege of Pet Sciences, Jiangsu Agri-Animal Husbandry Vocational College, Taizhou 225300, China.
Ting MengCollege of Pet Sciences, Jiangsu Agri-Animal Husbandry Vocational College, Taizhou 225300, China.
Lizhi LuZhejiang Provincial Key Laboratory of Livestock and Poultry Biotech Breeding, Key Laboratory of Livestock and Poultry Resources (Poultry) Evaluation and Utilization, Ministry of Agriculture and Rural Affairs, State Key Laboratory for Quality and Safety of Agro-Products, Institute of Animal Science & Veterinary, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.

Funding

China Agriculture Research System of MOF and MARA CARS-42-6; CARS-42-39Jiangsu Agri-animal Husbandry Vocational College Research Program NSF2023CB13National Natural Science Foundation of China 32172688Zhejiang Science and Technology Major Program on Agricultural New Variety Breeding 2021C02068-10
6 · The paper itself

Abstract

Apigenin and sodium butyrate have been reported to help alleviate oxidative stress. This study evaluated the jejunal transcriptomic responses in ducks receiving apigenin and sodium butyrate supplementation under oxidative stress. In total, 200 healthy 300-day-old female Jinyun Ma ducks (1.53 kg ± 0.15) were randomly divided into four groups, with five replicates per group. The groups were as follows: a control group (CON): ducks were fed a basal diet with sterile saline injection; a diquat-injection (DIQ) group: ducks were fed a basal diet with diquat injection; an apigenin plus diquat group (API): ducks were fed a basal diet containing apigenin (500 mg/kg) with diquat injection; and a sodium butyrate plus diquat group (SB): ducks were fed a basal diet containing sodium butyrate (500 mg/kg) with diquat injection. The injection dose of diquat is 8 mg/kg body weight. Analysis revealed that the dietary supplementation of apigenin and sodium butyrate reduced malondialdehyde (MDA) levels and increased total antioxidant capacity (T-AOC) (

Indexed as

diquatfeed additivejejunal morphologyJinyun Ma ducksoxidative injury

Identifiers

PMID40711315
PMCPMC12299872

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.