Evidence map›Paper›PMID 40711299›Full record

ArticleVeterinary sciences2025

Comparative Evaluation of Diagnostic Tests for Brucellosis in Humans and Animals: A Meta-Analytical Approach.

Shahid Nazir, Muhammad Farooq, Raheel Khan, Aman Ullah Khan, Ali Husnain, Muhammad Ali Hassan, Hosny El-Adawy, Heinrich Neubauer

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Seroprevalence and Antibody Magnitude ofVeterinary sciences · 2026
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shahid NazirDepartment of Pathobiology, University of Veterinary and Animal Sciences, Lahore, Sub-Campus Jhang, Jhang 35200, Pakistan.ORCID 0009-0006-1877-3724
Muhammad FarooqDepartment of Clinical Sciences, University of Veterinary and Animal Sciences, Lahore, Sub-Campus Jhang, Jhang 35200, Pakistan.ORCID 0000-0002-8771-3219
Raheel KhanDepartment of Clinical Sciences, University of Veterinary and Animal Sciences, Lahore, Sub-Campus Jhang, Jhang 35200, Pakistan.
Aman Ullah KhanDepartment of Pathobiology, University of Veterinary and Animal Sciences, Lahore, Sub-Campus Jhang, Jhang 35200, Pakistan.ORCID 0000-0002-5616-7833
Ali HusnainDepartment of Theriogenology, University of Veterinary and Animal Sciences, Lahore 54000, Pakistan.ORCID 0000-0001-7204-6225
Muhammad Ali HassanDepartment of Pathobiology, University of Veterinary and Animal Sciences, Lahore, Sub-Campus Jhang, Jhang 35200, Pakistan.
Hosny El-AdawyInstitute of Bacterial Infections and Zoonoses, Friédrich-Loeffler-Institut, 07743 Jena, Germany.ORCID 0000-0002-8585-4237
Heinrich NeubauerInstitute of Bacterial Infections and Zoonoses, Friédrich-Loeffler-Institut, 07743 Jena, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brucellosis is a highly contagious, neglected, and re-emerging zoonotic bacterial disease that poses significant health and economic challenges globally for both humans and animals. Extensive literature is available for various diagnostic strategies; however, no comprehensive meta-analysis comparing the diagnostic tests used has been published. The present study aimed to estimate the relative risk (RR) of diagnostic tests used in humans and animals published between 2013 and 2023. Four databases were systematically searched, and the articles were screened using predefined inclusion and exclusion criteria. Ultimately, the screening process resulted in a total of 135 studies, including 328 comparisons of relevant data of 19,921 humans and 64,145 animals. The data from these studies were extracted, and the subgroup meta-analyses were conducted using the METABIN procedure in the "meta" package of the R statistical software (version 4.4.1). The forest plots were generated to estimate RR, and the funnel plots were used to assess publication and report bias. The subgroup analysis revealed that primary binding assays had higher comparative detection rates than the Rose Bengal plate test (RBPT) for brucellosis in humans [RR = 1.75 (95% CI: 1.35-2.26),

Indexed as

Brucellabrucellosisdiagnosismeta-analysistests comparison

Identifiers

PMID40711299
PMCPMC12298791

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.