Evidence map›Paper›PMID 40711193›Full record

ReviewNanomaterials (Basel, Switzerland)2025

Multifunctional Upconversion Nanoparticles Transforming Photoacoustic Imaging: A Review.

Yuqian Zhang, Zerui Li, Ziqing Du, Jianming Pan, Yanan Huang

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuqian ZhangNepean Hospital, Kingswood, NSW 2747, Australia.
Zerui LiSchool of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, China.
Ziqing DuSchool of Materials Science and Engineering, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0009-0001-9660-0638
Jianming PanSchool of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, China.
Yanan HuangSchool of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0002-0509-7433

Funding

National Natural Science Foundation of China 22308127National Natural Science Foundation of China U22A20413
6 · The paper itself

Abstract

Photoacoustic imaging (PAI) merges the high spatial resolution of optical methods with the deep tissue penetration provided by ultrasound, making it a valuable tool in biomedical imaging. In recent years, a diverse array of photoacoustic contrast agents, spanning both organic and inorganic materials, has been developed. Among them, upconversion nanoparticles (UCNPs) stand out as promising candidates due to their unique optical features, tunable absorption in the near-infrared I (NIR-I, 750-1350 nm) region, and strong potential for both imaging and treatment-related uses. This review discusses the growing significance of UCNPs in the field of PAI, focusing on their structural characteristics, strengths, and existing challenges. Then, we talk about an up-to-date account of the current literature on the use of UCNPs as contrast agents for PAI. Lastly, we discuss the challenges and perspectives of UCNPs as a contrast agent for PAI in preclinical research and clinical diagnosis.

Indexed as

contrast agentslanthanide ions doped nanoparticlesNIR absorptionphotoacoustic imagingupconversion nanoparticles

Identifiers

PMID40711193
PMCPMC12300657

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.