Evidence map›Paper›PMID 40711148›Full record

ArticleToxins2025

Chae Hyun Lee, Sangsu Shin, Tae Hyun Kim, Sang In Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chae Hyun LeeDepartment of Animal Science and Biotechnology, Kyungpook National University, Sangju 37224, Republic of Korea.ORCID 0009-0008-4523-013X
Sangsu ShinDepartment of Animal Science and Biotechnology, Kyungpook National University, Sangju 37224, Republic of Korea.
Tae Hyun KimDepartment of Animal Science, The Pennsylvania State University, University Park, PA 16802, USA.
Sang In LeeDepartment of Animal Science and Biotechnology, Kyungpook National University, Sangju 37224, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patulin (PAT) is a mycotoxin commonly found in fruits and contaminated feedstuffs, known for its gastrointestinal and systemic toxicity. However, the mechanisms underlying PAT-induced damage to intestinal epithelial cells remain poorly understood. In this study, we demonstrated that 6.5 µM PAT exposure for 24 h reduced glutamine (GLN) uptake and altered the expression of GLN transporters and related metabolic enzymes in IPEC-J2 cells. This concentration was selected based on previous in vitro studies that reported PAT-induced cytotoxicity in porcine intestinal epithelial cells. Moreover, PAT also upregulated ER stress markers (

Indexed as

Epithelial CellsGlutamineIntestinal MucosaIntestine, SmallPatulinAnimalsCell LineCytokinesEndoplasmic Reticulum StressStress, PhysiologicalSwineCytokinesGlutaminePatulinER stressglutamine metabolisminflammationintestinal epithelial barriernatural productsNymphoides peltatapatulin

Identifiers

PMID40711148
PMCPMC12299487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.