Evidence map›Paper›PMID 40711138›Full record

ArticleToxins2025

Botulinum Neurotoxin A-Induced Muscle Morphology Changes in Children with Cerebral Palsy: A One-Year Follow-Up Study.

Charlotte Lambrechts, Nathalie De Beukelaer, Ines Vandekerckhove, Ineke Verreydt, Anke Andries, Francesco Cenni, Ghislaine Gayan-Ramirez, Kaat Desloovere, Anja Van Campenhout

Abstract read
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Charlotte LambrechtsDepartment of Rehabilitation Sciences, Neurorehabilitation Research Group, KU Leuven, 3000 Leuven, Belgium.ORCID 0009-0007-6720-0727
Nathalie De BeukelaerDepartment of Rehabilitation Sciences, Neurorehabilitation Research Group, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-7800-3354
Ines VandekerckhoveDepartment of Rehabilitation Sciences, Neurorehabilitation Research Group, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-6023-3004
Ineke VerreydtDepartment of Rehabilitation Sciences, Neurorehabilitation Research Group, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-6575-440X
Anke AndriesDepartment of Chronic Diseases and Metabolism, Laboratory of Respiratory Diseases and Thoracic Surgery, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-7971-8079
Francesco CenniDepartment of Clinical and Experimental Sciences, University of Brescia, 25121 Brescia, Italy.ORCID 0000-0001-8637-8853
Ghislaine Gayan-RamirezDepartment of Chronic Diseases and Metabolism, Laboratory of Respiratory Diseases and Thoracic Surgery, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-9652-7437
Kaat DesloovereDepartment of Rehabilitation Sciences, Neurorehabilitation Research Group, KU Leuven, 3000 Leuven, Belgium.
Anja Van CampenhoutDepartment of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-8158-5535

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Botulinum neurotoxin type A (BoNT-A) is widely used to reduce spasticity in children with cerebral palsy. Despite its therapeutic benefits, incomplete muscle recovery has been observed post-treatment. This study evaluated longitudinal BoNT-A effects on muscle morphology over one year in children with CP (

Indexed as

Botulinum Toxins, Type ACerebral PalsyMuscle, SkeletalNeuromuscular AgentsChildChild, PreschoolFemaleFollow-Up StudiesHumansMaleUltrasonographyBotulinum Toxins, Type ANeuromuscular Agentsbotulinum neurotoxin type Acerebral palsymuscle growthmuscle imaging

Identifiers

PMID40711138
PMCPMC12299369

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.