Evidence map›Paper›PMID 40711127›Full record

ArticleToxins2025

Occurrence of Aflatoxin M

Andrin Tahiri, Josif Risto, Lorena Mato, Alma Cani, Dritan Topi

Abstract read
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrin TahiriMedical Service of Toxicology and Addictology, 'Mother Teresa' University Hospital Center, 1000 Tirana, Albania.
Josif RistoDepartment of Pharmacy, Faculty of Medical Sciences, Luarasi University, Rruga e Elbasanit Street, 1003 Tirana, Albania.
Lorena MatoDepartment of Chemistry, Faculty of Natural Sciences, University of Tirana, Blvd. Zogu 1, No. 25, 1001 Tirana, Albania.
Alma CaniDepartment of Surgery, Faculty of Medicine, University of Medicine, Tirana (UMT), 1000 Tirana, Albania.
Dritan TopiDepartment of Chemistry, Faculty of Natural Sciences, University of Tirana, Blvd. Zogu 1, No. 25, 1001 Tirana, Albania.ORCID 0000-0001-7852-5374

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the prevalence of aflatoxin M1 (AFM1) in milk marketed in Tirana, Albania, along with dietary exposure and associated potential health risks. The World Health Organization has categorized Albania in cluster G02 of GEMS/FOOD, highlighting that milk is a staple in the Albanian diet, which points to a possible health risk. A total of 141 milk samples, comprising both Ultra-High Temperature (UHT) and pasteurized types, were collected from local markets in Tirana and analyzed from March 2023 to February 2024. The determination of AFM1 levels was carried out using High-Pressure Liquid Chromatography with a Fluorescence Detector (HPLC-FLD), a precise and dependable technique for identifying and measuring aflatoxins in food products. Aflatoxin M1 was found in 62.4% of the milk samples, with 26.2% surpassing the European Union's maximum residue levels (MRL). The mean AFM1 concentrations were 58.8 ± 95.8 ng/kg, reaching a maximum level of 399.0 ng/kg. The Estimated Daily Intake (EDI) for various groups-toddlers, children, adolescents, and adults-was determined to be 2.161, 1.297, 0.519, and 0.370 ng/kg of body weight per day, respectively. The Hazard Index (HI), derived from the AFM1 exposure for four population groups, was 10.81 (toddlers), 6.48 (children), 2.59 (adolescents), and 1.85 (adults). The Margin of Exposure (MoE) was 1.85, 3.08, 7.71, and 10.81, respectively. The incidence of hepatocellular carcinoma (HCC) per 100,000 people in the four groups was 0.034, 0.021, 0.008, and 0.006, respectively. The study is the first comprehensive evaluation of AFM1 prevalence, highlighting the potential risks associated with milk consumption, as milk is a dietary staple in Albanian households. It addresses a critical public health concern regarding aflatoxin M1 (AFM1) contamination in milk consumed in Tirana, Albania, by highlighting the need for ongoing monitoring, regulatory measures, and educational outreach to enhance food safety and safeguard public health in Albania, as well as in other regions facing similar concerns.

Indexed as

Aflatoxin M1Food ContaminationMilkAdolescentAdultAlbaniaAnimalsChildChild, PreschoolDietary ExposureHumansInfantRisk AssessmentAflatoxin M1aflatoxin M1Albaniaexposure assessmentHPLC-FLDmilkrisk assessment

Identifiers

PMID40711127
PMCPMC12299339

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.