Evidence map›Paper›PMID 40711125›Full record

ReviewToxins2025

The Therapeutic Potential of Antimicrobial Peptides Isolated from the Skin Secretions of Anurans of the Genus

Priscila Mendes Ferreira, Fabiano Fagundes Moser da Silva, Joyce Silva Dos Santos, Brunna de Oliveira Silva, Carlos José Correia de Santana, Osmindo Rodrigues Pires Júnior, Wagner Fontes, Mariana S Castro

Abstract readReview
In one paragraph

Review in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Priscila Mendes FerreiraLaboratory of Toxinology, Physiological Sciences Department, Biological Sciences Institute, University of Brasilia, Brasilia 70910-900, DF, Brazil.
Fabiano Fagundes Moser da SilvaLaboratory of Toxinology, Physiological Sciences Department, Biological Sciences Institute, University of Brasilia, Brasilia 70910-900, DF, Brazil.ORCID 0000-0003-3866-696X
Joyce Silva Dos SantosLaboratory of Toxinology, Physiological Sciences Department, Biological Sciences Institute, University of Brasilia, Brasilia 70910-900, DF, Brazil.
Brunna de Oliveira SilvaLaboratory of Toxinology, Physiological Sciences Department, Biological Sciences Institute, University of Brasilia, Brasilia 70910-900, DF, Brazil.
Carlos José Correia de SantanaLaboratory of Toxinology, Physiological Sciences Department, Biological Sciences Institute, University of Brasilia, Brasilia 70910-900, DF, Brazil.ORCID 0000-0001-9781-3670
Osmindo Rodrigues Pires JúniorLaboratory of Toxinology, Physiological Sciences Department, Biological Sciences Institute, University of Brasilia, Brasilia 70910-900, DF, Brazil.ORCID 0000-0002-9875-9407
Wagner FontesLaboratory of Protein Chemistry and Biochemistry, Cellular Biology Department, Biological Sciences Institute, University of Brasilia, Brasilia 70910-900, DF, Brazil.ORCID 0000-0001-5140-8573
Mariana S CastroLaboratory of Toxinology, Physiological Sciences Department, Biological Sciences Institute, University of Brasilia, Brasilia 70910-900, DF, Brazil.ORCID 0000-0001-5143-152X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microorganisms play a dual role in human health, serving as both essential allies and serious threats. Their association with infections led to the development of antimicrobials like penicillin, which revolutionized medicine. However, the emergence of antimicrobial resistance (AMR) has created a global health crisis, rendering many treatments ineffective due to pathogen mutations and acquired resistance mechanisms, particularly among ESKAPE pathogens. This resistance increases morbidity, mortality, and healthcare costs, exacerbated by antibiotic overuse and globalization. Biofilms and sepsis further complicate treatment. Addressing AMR requires new therapies, rational antibiotic use, and innovative approaches for drug discovery. Coordinated global action is essential to ensure future access to effective treatments. Antimicrobial peptides (AMPs) derived from

Indexed as

Anti-Bacterial AgentsAntimicrobial PeptidesAnuraSkinAnimalsBacteriaHumansAnti-Bacterial AgentsAntimicrobial Peptidesantimicrobial peptidesantimicrobial resistance crisisAnuransBoanaskin secretiontherapeutic properties

Identifiers

PMID40711125
PMCPMC12297880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.