Evidence map›Paper›PMID 40711060›Full record

ReviewTropical medicine and infectious disease2025

Impact of Human Granulocytic Anaplasmosis in Spain from 1997 to 2022.

Hugo Almeida, Montserrat Alonso-Sardón, Beatriz Rodríguez-Alonso, Amparo López-Bernus, Ángela Romero-Alegría, Virginia Velasco-Tirado, Antonio Muro, Moncef Belhassen-García

Abstract readReview
In one paragraph

Review in Tropical medicine and infectious disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hugo AlmeidaServicio de Medicina Interna, Hospital Universitario de Salamanca (HUS), Centro de Investigación de Enfermedades Tropicales de la Universidad de Salamanca (CIETUS), Instituto de Investigación Biomédica de Salamanca (IBSAL), Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0001-5454-1249
Montserrat Alonso-SardónÁrea de Medicina Preventiva, Epidemiología y Salud Pública, Facultad de Medicina, Centro de Investigación de Enfermedades Tropicales de la Universidad de Salamanca, Instituto de Investigación Biomédica de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0003-1829-5858
Beatriz Rodríguez-AlonsoServicio de Medicina Interna, Hospital Universitario de Salamanca, Centro de Investigación de Enfermedades Tropicales de la Universidad de Salamanca, Instituto de Investigación Biomédica de Salamanca, 37007 Salamanca, Spain.
Amparo López-BernusServicio de Medicina Interna, Unidad de Enfermedades Infecciosas, HUS, CIETUS, IBSAL, 37007 Salamanca, Spain.ORCID 0000-0002-7524-4056
Ángela Romero-AlegríaServicio de Medicina Interna, Hospital Universitario de Salamanca, Centro de Investigación de Enfermedades Tropicales de la Universidad de Salamanca, Instituto de Investigación Biomédica de Salamanca, 37007 Salamanca, Spain.
Virginia Velasco-TiradoServicio de Dermatología, Hospital Universitario de Salamanca, Centro de Investigación de Enfermedades Tropicales de la Universidad de Salamanca, Instituto de Investigación Biomédica de Salamanca, 37007 Salamanca, Spain.
Antonio MuroGrupo de Enfermedades Infecciosas y Tropicales (e-INTRO), Centro de Investigación de Enfermedades Tropicales de la Universidad de Salamanca, Instituto de Investigación Biomédica de Salamanca, Facultad de Farmacia, Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0003-0244-4740
Moncef Belhassen-GarcíaServicio de Medicina Interna, Unidad de Infecciosas, Hospital Universitario de Salamanca, Centro de Investigación de Enfermedades Tropicales de la Universidad de Salamanca, Instituto de Investigación Biomédica de Salamanca, Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0002-2230-1256

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human granulocytic anaplasmosis (HGA) is an emerging zoonosis in Europe, with limited data available from Spain. This study aimed to quantify HGA cases in the Spanish National Health System over the last 26 years, assess its evolution, and evaluate the impact in terms of hospital stay and cost. A retrospective observational case series was conducted using the Minimal Basic Data Set (MBDS, CMBD in Spanish). Hospitalized patients with ICD-9-CM and ICD-10 codes for anaplasmosis from 1997 to 2022 were included. Ten HGA cases were reported. The incidence remained stable at one case per year [IR = 0.021 cases/million person-years], except in 2018 [IR = 0.048]. Six patients (60%) were men, with a mean age of 49 years (±20.9). Hospital stays ranged from 3 to 13 days. The total cost was EUR 45,540.57, with an average cost of EUR 4554.06 (±1032.16) per case. All patients had favorable outcomes. HGA has a low incidence in Spain, with moderate associated costs. Despite its emergence, its economic and health impact remains manageable, underscoring the effectiveness of Spain's healthcare system. Continued surveillance and prevention are essential to address evolving vector-borne diseases.

Indexed as

epidemiologyhuman granulocytic anaplasmosisSpaintick-borne diseaseszoonosis

Identifiers

PMID40711060
PMCPMC12298059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.