Evidence map›Paper›PMID 40711021›Full record

ReviewToxics2025

Neonicotinoid-Induced Cytotoxicity: Insights into Cellular Mechanisms and Health Risks.

Yuqing Ma, Qiangwei Wang

Abstract readReview
In one paragraph

Review in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yuqing MaMinistry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Zhejiang Key Laboratory of Biology and Ecological Regulation of Crop Pathogens and Insects, Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou 310058, China.
Qiangwei WangMinistry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Zhejiang Key Laboratory of Biology and Ecological Regulation of Crop Pathogens and Insects, Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0001-5222-846X

Funding

National Natural Science Foundation of China 22176173
6 · The paper itself

Abstract

Neonicotinoids are extensively used in agricultural production, yet increasing evidence highlights their cytotoxic effects on various cell types. Research has demonstrated that these pesticides can significantly impair the viability and function of reproductive, adipose, neural, immune, and epithelial cells. The underlying mechanisms involve metabolic disturbances, mitochondrial dysfunction, and oxidative stress. These cellular effects raise serious concerns about the potential risks neonicotinoids pose to both human health and the environment. Further investigation is essential to fully understand their toxicological impact and to inform safer pesticide regulation and use.

Indexed as

cytotoxicityhuman health riskmitochondrial dysfunctionneonicotinoidsoxidative stress

Identifiers

PMID40711021
PMCPMC12300005

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.