Evidence map›Paper›PMID 40711004›Full record

ReviewToxics2025

Research Progress on Chemical Compositions, Pharmacological Activities, and Toxicities of Quinone Compounds in Traditional Chinese Medicines.

Zhe Li, Rui Yao, Hong Guo, Wenguang Jing, Xiaohan Guo, Xiaoqiu Liu, Yingni Pan, Pei Cao, Lei Zhang, Jianbo Yang and 2 more

Abstract readReview
In one paragraph

Review in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Chemical and Biological Investigation of the EndophyticJournal of fungi (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhe LiSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Benxi 117004, China.
Rui YaoSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Benxi 117004, China.
Hong GuoNational Institutes for Food and Drug Control, Beijing 102629, China.
Wenguang JingNational Institutes for Food and Drug Control, Beijing 102629, China.ORCID 0009-0001-5122-523X
Xiaohan GuoNational Institutes for Food and Drug Control, Beijing 102629, China.
Xiaoqiu LiuSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Benxi 117004, China.
Yingni PanSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Benxi 117004, China.
Pei CaoChina National Center for Food Safety Risk Assessment, Beijing 100020, China.ORCID 0000-0002-7599-8982
Lei ZhangChina National Center for Food Safety Risk Assessment, Beijing 100020, China.
Jianbo YangNational Institutes for Food and Drug Control, Beijing 102629, China.ORCID 0000-0002-1368-5294
Xianlong ChengNational Institutes for Food and Drug Control, Beijing 102629, China.
Feng WeiNational Institutes for Food and Drug Control, Beijing 102629, China.ORCID 0000-0002-7598-0723

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the continuous development of research on natural medicines, quinone compounds have become increasingly important in the research field of chemical constituents of natural treatments. However, there is a lack of in-depth and systematic collation of their types, distribution, pharmacological activities, and potential toxicities. This article comprehensively reviews the structural types, biogenetic pathways, extraction and separation methods, structural identification techniques, pharmacological activities, and toxicities of quinone compounds. It is found that the main difficulties in the research of quinone compounds lie in the cumbersome traditional separation and structural identification processes, as well as the insufficient in-depth studies on the mechanisms of their activities and toxicities. This review aims to provide a reference for research on quinone compounds in natural products and offer ideas and suggestions for subsequent in-depth exploration of the pharmacological activities of quinone compounds, prevention and control of their toxicities, and the realization of rational drug use.

Indexed as

chemical componentspharmacological activitiesquinonessynthetic pathwaytoxicity

Identifiers

PMID40711004
PMCPMC12298499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.