Evidence map›Paper›PMID 40710770›Full record

ReviewJournal of cardiovascular development and disease2025

Iatrogenic Pneumopericardium After Pericardiocentesis: A Systematic Review and Case Report.

Andreas Merz, Hong Ran, Cheng-Ying Chiu, Henryk Dreger, Daniel Armando Morris, Matthias Schneider-Reigbert

Abstract readReview
In one paragraph

Review in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andreas MerzDeutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, 13353 Berlin, Germany.
Hong RanDepartment of Echocardiography, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Cheng-Ying ChiuDeutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, 13353 Berlin, Germany.ORCID 0000-0002-7075-1446
Henryk DregerDeutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, 13353 Berlin, Germany.ORCID 0000-0003-1909-4329
Daniel Armando MorrisDeutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, 13353 Berlin, Germany.ORCID 0000-0001-8655-7691
Matthias Schneider-ReigbertDeutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, 13353 Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPneumopericardium is the presence of air within the pericardial cavity. We report a case of iatrogenic pneumopericardium following pericardiocentesis in a patient with primary cardiac angiosarcoma. Additionally, we provide a systematic review of pericardiocentesis-associated pneumopericardium to offer a comprehensive overview and evaluate the role of echocardiography in its diagnosis.

methodsThe PubMed database was searched from inception until January 2025 to perform a systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to evaluate articles on iatrogenic pneumopericardium following pericardiocentesis published in the English language. The Joanna Briggs Institute (JBI) Critical Appraisal Checklist for Case Reports was used to appraise the included case reports.

resultsOf the 108 search results obtained, after screening and a backward citation search, 37 articles were selected for inclusion in this review, accounting for a total of 37 patients. According to the JBI Critical Appraisal Checklist for Case Reports, 7 case reports were of high quality and 12 of low quality. The overall evidence of quality of the case reports was moderate, and 51.6% of patients developed hemodynamic compromise or showed signs of cardiac tamponade. The main underlying cause for the development of pneumopericardium was issues relating to the catheter drainage system; 64.9% of cases required decompressive therapy.

conclusionsPneumopericardium can occur as a complication after pericardiocentesis and must therefore be considered in symptomatic patients. While detection by transthoracic echocardiography is difficult and relies on non-validated signs, chest X-ray and computed tomography can provide a definitive diagnosis.

Indexed as

air gapcase reportechocardiographypericardiocentesispneumopericardiumswirling bubblesystematic review

Identifiers

PMID40710770
PMCPMC12295399

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.