Evidence map›Paper›PMID 40710768›Full record

ArticleJournal of cardiovascular development and disease2025

Impact of the Presence of Chronic Total Occlusions on the Survival of Patients Treated with Coronary Artery Bypass Grafting.

Albi Fagu, Joseph Kletzer, Franziska Marie Ernst, Laurin Micek, Stoyan Kondov, Maximilian Kreibich, Clarence Pingpoh, Matthias Siepe, Martin Czerny, Tim Berger

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Albi FaguDepartment of Cardiovascular Surgery, University Heart Center Freiburg-Bad Krozingen, University Medical Center Freiburg, 79106 Freiburg, Germany.ORCID 0000-0002-9317-4303
Joseph KletzerDepartment of Cardiovascular Surgery, University Heart Center Freiburg-Bad Krozingen, University Medical Center Freiburg, 79106 Freiburg, Germany.
Franziska Marie ErnstDepartment of Cardiovascular Surgery, University Heart Center Freiburg-Bad Krozingen, University Medical Center Freiburg, 79106 Freiburg, Germany.
Laurin MicekDepartment of Cardiovascular Surgery, University Heart Center Freiburg-Bad Krozingen, University Medical Center Freiburg, 79106 Freiburg, Germany.
Stoyan KondovDepartment of Cardiovascular Surgery, University Heart Center Freiburg-Bad Krozingen, University Medical Center Freiburg, 79106 Freiburg, Germany.ORCID 0000-0002-1892-1487
Maximilian KreibichDepartment of Cardiovascular Surgery, University Heart Center Freiburg-Bad Krozingen, University Medical Center Freiburg, 79106 Freiburg, Germany.ORCID 0000-0003-3099-7254
Clarence PingpohDepartment of Cardiovascular Surgery, University Heart Center Freiburg-Bad Krozingen, University Medical Center Freiburg, 79106 Freiburg, Germany.
Matthias SiepeDepartment of Cardiac Surgery, University Hospital Bern, University of Bern, 3012 Bern, Switzerland.ORCID 0000-0003-3305-9343
Martin CzernyDepartment of Cardiovascular Surgery, University Heart Center Freiburg-Bad Krozingen, University Medical Center Freiburg, 79106 Freiburg, Germany.
Tim BergerDepartment of Cardiovascular Surgery, University Heart Center Freiburg-Bad Krozingen, University Medical Center Freiburg, 79106 Freiburg, Germany.ORCID 0000-0001-6263-9123

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although chronic total occlusions (CTO) are a common finding in patients treated with coronary artery bypass grafting (CABG), it is still not clear how their presence impacts the long-term outcomes achieved with surgery. We aimed to investigate the impact of CTO on the long-term results of patients with coronary artery disease who underwent CABG. Patients from 2005 to 2023 operated on at the University Hospital Freiburg-Bad Krozingen were analyzed. The primary outcome was all-cause mortality after 3-, 5-, and 10 years. The secondary outcome was the need for coronary reintervention in the follow-up period. Propensity score matching and multivariable Cox regression were performed, and Kaplan-Meier curves were used to graphically display the outcomes for the two groups. Of the 3424 patients included in the analysis, 1784 (52%) were categorized as CTO and 1640 (48%) were categorized as no-CTO. After propensity scoring, 1232 pairs were successfully matched. The 3-, 5-, and 10-year all-cause mortality was significantly higher in patients with CTO (

Indexed as

chronic total occlusion (CTO)coronary artery bypass grafting (CABG)coronary revascularization

Identifiers

PMID40710768
PMCPMC12295936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.